AIM: The aim of this study was to assess the adiponectin and visfatin concentrations in small-for-gestational age (SGA), appropriate-for-gestational age (AGA), and large-for-gestational age (LGA) newborns and their mothers. Sixty parturients giving birth to 20 term AGA singleton infants, 20 term singleton SGA infants, and 20 term singleton LGA infants were included into the study. RESULTS: Mean visfatin levels were found significantly higher in the SGA (p < 0.001) and LGA (p < 0.001) groups, and adiponectin levels were found significantly lower in the SGA group (p < 0.001) when compared with the AGA group. The SGA and LGA groups had higher insulin concentrations and HOMA-IR in comparison with the AGA group. The visfatin, glucose levels, and HOMA-IR (p < 0.001, p < 0.001, and p: 0.002, respectively) were higher in the LGA group than SGA group. CONCLUSION: We found significantly higher insulin and visfatin levels in LGA neonates and lower adiponectin levels in SGA neonates. We concluded that the relationship between adiponectin and visfatin and insulin sensitivity (metabolic disturbances) is very complex with little evidence of correlation in SGA and LGA neonates.
AIM: The aim of this study was to assess the adiponectin and visfatin concentrations in small-for-gestational age (SGA), appropriate-for-gestational age (AGA), and large-for-gestational age (LGA) newborns and their mothers. Sixty parturients giving birth to 20 term AGA singleton infants, 20 term singleton SGA infants, and 20 term singleton LGA infants were included into the study. RESULTS: Mean visfatin levels were found significantly higher in the SGA (p < 0.001) and LGA (p < 0.001) groups, and adiponectin levels were found significantly lower in the SGA group (p < 0.001) when compared with the AGA group. The SGA and LGA groups had higher insulin concentrations and HOMA-IR in comparison with the AGA group. The visfatin, glucose levels, and HOMA-IR (p < 0.001, p < 0.001, and p: 0.002, respectively) were higher in the LGA group than SGA group. CONCLUSION: We found significantly higher insulin and visfatin levels in LGA neonates and lower adiponectin levels in SGA neonates. We concluded that the relationship between adiponectin and visfatin and insulin sensitivity (metabolic disturbances) is very complex with little evidence of correlation in SGA and LGA neonates.
Authors: Dustin T Yates; Jessica L Petersen; Ty B Schmidt; Caitlin N Cadaret; Taylor L Barnes; Robert J Posont; Kristin A Beede Journal: J Anim Sci Date: 2018-06-29 Impact factor: 3.159
Authors: Elizabeth A DuPriest; Baoyu Lin; Philipp Kupfer; Kaiu Sekiguchi; Amruta Bhusari; Alexandra Quackenbush; Almir Celebic; Terry K Morgan; Jonathan Q Purnell; Susan P Bagby Journal: Am J Physiol Regul Integr Comp Physiol Date: 2018-06-20 Impact factor: 3.619
Authors: E A DuPriest; P Kupfer; B Lin; K Sekiguchi; T K Morgan; K E Saunders; T T Chatkupt; O N Denisenko; J Q Purnell; S P Bagby Journal: J Dev Orig Health Dis Date: 2012-06 Impact factor: 2.401