Literature DB >> 2048676

Serum bupivacaine concentrations following wound infiltration in children undergoing inguinal herniotomy.

K A Mobley1, J G Wandless, D Fell.   

Abstract

Serum bupivacaine concentrations were measured in 12 children who underwent elective herniotomy and who received analgesia in the form of wound infiltration. Mean (SD) peak concentration was 0.36 (0.14) micrograms/ml and time to peak concentration was 14.6 (7.2) minutes after infiltration of 1.25 mg/kg of bupivacaine. These concentrations are lower than those associated with other local anaesthetic blocks and well below potentially toxic levels. Wound infiltration provides a simple, effective and safe method of providing postoperative analgesia for hernia repair in children.

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Year:  1991        PMID： 2048676     DOI： 10.1111/j.1365-2044.1991.tb11697.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN： 0003-2409            Impact factor:   6.955


  2 in total

1.  Plasma concentrations of bupivacaine after wound infiltration of an 0.5% solution after inguinal herniorrhaphy: a preliminary study.

Authors:  H Kastrissios; E J Triggs; F Sinclair; P Moran; M Smithers
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

2.  The pharmacokinetics and safety of an intraoperative bupivacaine-collagen implant (XaraColl(®)) for postoperative analgesia in women following total abdominal hysterectomy.

Authors:  Susan L Cusack; Philip Reginald; Lisa Hemsen; Emmanuel Umerah
Journal:  J Pain Res       Date:  2013-03-04       Impact factor: 3.133
  2 in total

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