OBJECTIVE: To characterize neuropsychiatric symptoms in a large group of individuals with severe traumatic brain injury (TBI) and to correlate these symptoms with demographic, clinical, and functional features. METHODS: The Neuropsychiatric Inventory (NPI), a frequently used scale to assess behavioral, emotional, and motivational disorders in persons with neurological diseases, was administered to a sample of 120 persons with severe TBI. Controls were 77 healthy subjects. RESULTS: A wide range of neuropsychiatric symptoms was found in the population with severe TBI: apathy (42%), irritability (37%), dysphoria/depressed mood (29%), disinhibition (28%), eating disturbances (27%), and agitation (24%). A clear relationship was also found with other demographic and clinical variables. CONCLUSION: Neuropsychiatric disorders constitute an important part of the comorbidity in populations with severe TBI. Our study emphasizes the importance of integrating an overall assessment of cognitive disturbances with a specific neuropsychiatric evaluation to improve clinical understanding and treatment of persons with TBI.
OBJECTIVE: To characterize neuropsychiatric symptoms in a large group of individuals with severe traumatic brain injury (TBI) and to correlate these symptoms with demographic, clinical, and functional features. METHODS: The Neuropsychiatric Inventory (NPI), a frequently used scale to assess behavioral, emotional, and motivational disorders in persons with neurological diseases, was administered to a sample of 120 persons with severe TBI. Controls were 77 healthy subjects. RESULTS: A wide range of neuropsychiatric symptoms was found in the population with severe TBI: apathy (42%), irritability (37%), dysphoria/depressed mood (29%), disinhibition (28%), eating disturbances (27%), and agitation (24%). A clear relationship was also found with other demographic and clinical variables. CONCLUSION:Neuropsychiatric disorders constitute an important part of the comorbidity in populations with severe TBI. Our study emphasizes the importance of integrating an overall assessment of cognitive disturbances with a specific neuropsychiatric evaluation to improve clinical understanding and treatment of persons with TBI.
Authors: Lauren J Carlson; Gina C Bao; Sonya Besagar; Jacob B Leary; Hannah L Radabaugh; Corina O Bondi; Anthony E Kline Journal: Neurosci Lett Date: 2018-06-06 Impact factor: 3.046
Authors: Patricia B de la Tremblaye; Darik A O'Neil; Megan J LaPorte; Jeffrey P Cheng; Joshua A Beitchman; Theresa Currier Thomas; Corina O Bondi; Anthony E Kline Journal: Neurosci Biobehav Rev Date: 2017-05-30 Impact factor: 8.989
Authors: Gina C Bao; Isabel H Bleimeister; Lydia A Zimmerman; JoDy L Wellcome; Peter J Niesman; Hannah L Radabaugh; Corina O Bondi; Anthony E Kline Journal: J Neurotrauma Date: 2019-01-09 Impact factor: 5.269
Authors: Kaitlin A Folweiler; Corina O Bondi; Elizabeth A Ogunsanya; Megan J LaPorte; Jacob B Leary; Hannah L Radabaugh; Christina M Monaco; Anthony E Kline Journal: J Neurotrauma Date: 2016-04-20 Impact factor: 5.269
Authors: Tessa Hart; Emma K T Benn; Emilia Bagiella; Patricia Arenth; Sureyya Dikmen; Dale C Hesdorffer; Thomas A Novack; Joseph H Ricker; Ross Zafonte Journal: J Neurotrauma Date: 2014-01-10 Impact factor: 5.269
Authors: Sarah Sullivan; Stuart H Friess; Jill Ralston; Colin Smith; Kathleen J Propert; Paul E Rapp; Susan S Margulies Journal: J Neurotrauma Date: 2013-04-03 Impact factor: 5.269
Authors: Kristine M Knutson; Olga Dal Monte; Vanessa Raymont; Eric M Wassermann; Frank Krueger; Jordan Grafman Journal: Hum Brain Mapp Date: 2013-02-13 Impact factor: 5.038
Authors: Thomas I Phelps; Corina O Bondi; Vincent V Mattiola; Anthony E Kline Journal: Neurorehabil Neural Repair Date: 2016-05-24 Impact factor: 3.919