Literature DB >> 20484567

A histoplasma capsulatum-specific IgG1 isotype monoclonal antibody, H1C, to a 70-kilodalton cell surface protein is not protective in murine histoplasmosis.

Livia Cristina Liporagi Lopes1, Allan J Guimarães, Mariana Duarte de Cerqueira, Beatriz L Gómez, Joshua D Nosanchuk.   

Abstract

Monoclonal antibodies to Histoplasma capsulatum can modify pathogenesis. We now show that monoclonal antibody H1C to a 70-kDa antigen increases intracellular fungal growth and reduces macrophage nitric oxide release but has no effect on fungal burden or survival in murine infection. This further demonstrates the complexities of host-pathogen interactions.

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Year:  2010        PMID： 20484567      PMCID： PMC2897255          DOI： 10.1128/CVI.00033-10

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  10 in total

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Authors:  David O Beenhouwer; Esther M Yoo; Chun-Wei Lai; Miguel A Rocha; Sherie L Morrison
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3.  Development of a novel antigen detection test for histoplasmosis.

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Review 4.  Antibody-mediated protection through cross-reactivity introduces a fungal heresy into immunological dogma.

Authors:  Arturo Casadevall; Liise-anne Pirofski
Journal:  Infect Immun       Date:  2007-08-20       Impact factor: 3.441

Review 5.  Antibody immunity and invasive fungal infections.

Authors:  A Casadevall
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6.  Disseminated histoplasmosis: clinical and pathologic correlations.

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Journal:  Medicine (Baltimore)       Date:  1980-01       Impact factor: 1.889

7.  Monoclonal antibodies to heat shock protein 60 alter the pathogenesis of Histoplasma capsulatum.

Authors:  Allan J Guimarães; Susana Frases; Francisco J Gomez; Rosely M Zancopé-Oliveira; Joshua D Nosanchuk
Journal:  Infect Immun       Date:  2009-01-29       Impact factor: 3.441

8.  Detection of the 70-kilodalton histoplasma capsulatum antigen in serum of histoplasmosis patients: correlation between antigenemia and therapy during follow-up.

Authors:  B L Gómez; J I Figueroa; A J Hamilton; S Diez; M Rojas; A Tobón; A Restrepo; R J Hay
Journal:  J Clin Microbiol       Date:  1999-03       Impact factor: 5.948

9.  Antibodies to a cell surface histone-like protein protect against Histoplasma capsulatum.

Authors:  Joshua D Nosanchuk; Judith N Steenbergen; Li Shi; George S Deepe; Arturo Casadevall
Journal:  J Clin Invest       Date:  2003-10       Impact factor: 14.808

10.  A monoclonal antibody to Histoplasma capsulatum alters the intracellular fate of the fungus in murine macrophages.

Authors:  Li Shi; Priscila C Albuquerque; Eszter Lazar-Molnar; Xintao Wang; Laura Santambrogio; Attila Gácser; Joshua D Nosanchuk
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  10 in total
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Journal:  Front Microbiol       Date:  2012-02-02       Impact factor: 5.640

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Review 7.  The Einstein-Brazil Fogarty: A decade of synergy.

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Review 8.  Monoclonal Antibodies as Tools to Combat Fungal Infections.

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Journal:  J Fungi (Basel)       Date:  2020-02-04

9.  Harnessing antifungal immunity in pursuit of a Staphylococcus aureus vaccine strategy.

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Journal:  PLoS Pathog       Date:  2020-08-20       Impact factor: 6.823
  9 in total

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