Literature DB >> 20483609

Synthesis of novel beta-lactam fused spiroisoxazolidine chromanones and tetralones as potent antimicrobial agent for human and plant pathogens.

Natarajan Arumugam1, Raghavachary Raghunathan, Vellaisamy Shanmugaiah, Narayanasamy Mathivanan.   

Abstract

Synthesis of novel beta-lactam fused spiroisoxazolidine chromanones and tetralones ring systems has been achieved by intermolecular 1,3-dipolar cycloaddition reaction of bicyclic nitrone with unusual dipolarophiles, arylidene chromanones/tetralones under different reaction conditions. The synthesized compounds were evaluated for antimicrobial activities. It was observed that two of the synthesized compounds exhibited relatively good antibacterial and antifungal activities. Copyright 2010 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20483609     DOI： 10.1016/j.bmcl.2010.04.084

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  Bioactivity Studies of β-Lactam Derived Polycyclic Fused Pyrroli-Dine/Pyrrolizidine Derivatives in Dentistry: In Vitro, In Vivo and In Silico Studies.

Authors:  Gowri Meiyazhagan; Rajesh Raju; Sofi Beaula Winfred; Bhavani Mannivanan; Hemadev Bhoopalan; Venkatesh Shankar; Sathiya Sekar; Deepa Parvathi Venkatachalam; Ravishankar Pitani; Venkateshbabu Nagendrababu; Malini Thaiman; Kandaswamy Devivanayagam; Jeyakanthan Jayaraman; Raghunathan Ragavachary; Ganesh Venkatraman
Journal:  PLoS One       Date:  2015-07-17       Impact factor: 3.240

2.  Regio and stereoselective synthesis of anticancer spirooxindolopyrrolidine embedded piperidone heterocyclic hybrids derived from one-pot cascade protocol.

Authors:  Natarajan Arumugam; Abdulrahman I Almansour; Raju Suresh Kumar; Dhaifallah M Al-Thamili; Govindasami Periyasami; V S Periasamy; Jegan Athinarayanan; Ali A Alshatwi; S M Mahalingam; J Carlos Menéndez
Journal:  Chem Cent J       Date:  2018-09-01       Impact factor: 4.215

3.  Multicomponent Domino Synthesis, Anticancer Activity and Molecular Modeling Simulation of Complex Dispirooxindolopyrrolidines.

Authors:  Natarajan Arumugam; Abdulrahman I Almansour; Raju Suresh Kumar; Periyasami Govindasami; Dhaifallah M Al-Thamili; Rajapandian Krishnamoorthy; Vaiyapuri Subbarayan Periasamy; Ali A Alshatwi; S M Mahalingam; Shankar Thangamani; J Carlos Menéndez
Journal:  Molecules       Date:  2018-05-05       Impact factor: 4.411

Review 4.  A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives.

Authors:  Paola Borrego-Muñoz; Felipe Ospina; Diego Quiroga
Journal:  Molecules       Date:  2021-06-30       Impact factor: 4.411
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.