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Literature DB >> 20483475

Mutation analysis of the C1QTNF3 gene in patients with schizophrenia.

Irina Bespalova¹, Gary Angelo, Benjamin Ritter, Enrique Rossy-Fullana, Jose Carrion-Baralt, Martina Durner, Jeremy Silverman.

Abstract

We previously identified a small region on chromosome 5p13 related to schizophrenia in a Puerto Rican pedigree. We screened one of the positional candidate genes, C1QTNF3, for mutations in affected family members. The direct sequencing identified 10 sequence variants, including five shared by all affected family members. Genotyping of the shared variants in a Puerto Rican sample of 118 cases and 136 controls did not reveal either allelic or genotype association with schizophrenia.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

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Year: 2010 PMID： 20483475 PMCID： PMC2925058 DOI： 10.1016/j.psychres.2009.10.011

Source DB: PubMed Journal: Psychiatry Res ISSN： 0165-1781 Impact factor: 3.222

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Mutation analysis of the C1QTNF3 gene in patients with schizophrenia.

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2. Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships.

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5. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys.

Review 6. Hyperglycemia associated with the use of atypical antipsychotics.

Review 7. Schizophrenia and comorbid metabolic disorders.

Review 8. Adipokines as regulators of muscle metabolism and insulin sensitivity.

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Review 10. Inflammation and schizophrenia.