Literature DB >> 20482501

Cyclodextrins: more than pharmaceutical excipients.

F J Otero-Espinar1, A Luzardo-Alvarez, J Blanco-Méndez.   

Abstract

Cyclodextrins are pharmaceutical excipients used to enhance the solubility, stability, safety and bioavailability of drugs. Recent findings have shown them to display adjuvant activity in vaccine therapy and prophylactic and therapeutic activity in the treatment of several host-pathogen infections. This article focuses on their activity and mechanism of action.

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Year:  2010        PMID： 20482501     DOI： 10.2174/138955710791572479

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  3 in total

1.  2-Hydroxypropyl-β-cyclodextrin Ototoxicity in Adult Rats: Rapid Onset and Massive Destruction of Both Inner and Outer Hair Cells Above a Critical Dose.

Authors:  Xiaopeng Liu; Dalian Ding; Guang-Di Chen; Li Li; Haiyan Jiang; Richard Salvi
Journal:  Neurotox Res       Date:  2020-06-30       Impact factor: 3.911

2.  Spatiotemporal Developmental Upregulation of Prestin Correlates With the Severity and Location of Cyclodextrin-Induced Outer Hair Cell Loss and Hearing Loss.

Authors:  Dalian Ding; Haiyan Jiang; Senthilvelan Manohar; Xiaopeng Liu; Li Li; Guang-Di Chen; Richard Salvi
Journal:  Front Cell Dev Biol       Date:  2021-05-24

3.  A novel cyclodextrin glycosyltransferase from Alkaliphilic Amphibacillus sp. NPST-10: purification and properties.

Authors:  Abdelnasser S S Ibrahim; Ali A Al-Salamah; Mohamed A El-Tayeb; Yahya B El-Badawi; Garabed Antranikian
Journal:  Int J Mol Sci       Date:  2012-08-22       Impact factor: 6.208
  3 in total

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