OBJECTIVE: To analyze outcomes following fat injection laryngoplasty in patients with unilateral vocal cord paralysis. DESIGN: Longitudinal outcomes evaluation study. SETTING: Tertiary referral voice center. PATIENTS: Thirty-three consecutive patients with unilateral vocal cord paralysis undergoing autologous fat injection laryngoplasty with preoperative and serial postoperative follow-up at Chang Gung Memorial Hospital, Taipei, Taiwan. INTERVENTION: Autologous fat injection laryngoplasty. MAIN OUTCOME MEASURES: Voice laboratory measurements, Voice Outcome Survey, and 36-item Short Form Health Survey. RESULTS: Except for the physical functioning dimension of global health, voice-related subjective outcomes and acoustic variables of the patients significantly improved after surgery (P < .05). Compared with population norms, the mean (SD) scores of patients were inferior on the 36-item Short Form Health Survey dimensions of physical functioning (80.7 [22.3] vs 90.2 [17.4]) and role functioning-physical problems (65.0 [36.2] vs 80.2 [36.2]). Overall, 88.9% (24 of 27) of the patients were satisfied with their surgery. CONCLUSIONS: Fat injection laryngoplasty seems to be effective in enhancing acoustic and quality of life outcomes in patients with unilateral vocal cord paralysis. The effect is sustainable over 12 months.
OBJECTIVE: To analyze outcomes following fat injection laryngoplasty in patients with unilateral vocal cord paralysis. DESIGN: Longitudinal outcomes evaluation study. SETTING: Tertiary referral voice center. PATIENTS: Thirty-three consecutive patients with unilateral vocal cord paralysis undergoing autologous fat injection laryngoplasty with preoperative and serial postoperative follow-up at Chang Gung Memorial Hospital, Taipei, Taiwan. INTERVENTION: Autologous fat injection laryngoplasty. MAIN OUTCOME MEASURES: Voice laboratory measurements, Voice Outcome Survey, and 36-item Short Form Health Survey. RESULTS: Except for the physical functioning dimension of global health, voice-related subjective outcomes and acoustic variables of the patients significantly improved after surgery (P < .05). Compared with population norms, the mean (SD) scores of patients were inferior on the 36-item Short Form Health Survey dimensions of physical functioning (80.7 [22.3] vs 90.2 [17.4]) and role functioning-physical problems (65.0 [36.2] vs 80.2 [36.2]). Overall, 88.9% (24 of 27) of the patients were satisfied with their surgery. CONCLUSIONS: Fat injection laryngoplasty seems to be effective in enhancing acoustic and quality of life outcomes in patients with unilateral vocal cord paralysis. The effect is sustainable over 12 months.
Authors: A Ricci Maccarini; M Stacchini; F Mozzanica; A Schindler; E Basile; G DE Rossi; P Woo; M Remacle; M Magnani Journal: Acta Otorhinolaryngol Ital Date: 2018-06 Impact factor: 2.124