Literature DB >> 20478440

The multiple roles of estrogens and the enzyme aromatase.

Wah Chin Boon1, Jenny D Y Chow, Evan R Simpson.   

Abstract

Aromatase is the enzyme that catalyzes the last step of estrogen biosynthesis. It is expressed in many tissues such as the gonads, brain and adipose tissue. The regulation of the level and activity of aromatase determines the levels of estrogens that have endocrine, paracrine and autocrine effects on tissues. Estrogens play many roles in the body, regulating reproduction, metabolism and behavior. In the brain, cell survival and the activity of neurons are affected by estrogens and hence aromatase.

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Year:  2010        PMID： 20478440     DOI： 10.1016/S0079-6123(08)81012-6

Source DB:  PubMed          Journal:  Prog Brain Res        ISSN： 0079-6123            Impact factor:   2.453


  60 in total

Review 1.  [Gender aspects in anesthesia : modified approach in research and treatment?].

Authors:  M Schopper; P I Bäumler; J Fleckenstein; D Irnich
Journal:  Anaesthesist       Date:  2012-04       Impact factor: 1.041

Review 2.  Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems.

Authors:  C A Frye; E Bo; G Calamandrei; L Calzà; F Dessì-Fulgheri; M Fernández; L Fusani; O Kah; M Kajta; Y Le Page; H B Patisaul; A Venerosi; A K Wojtowicz; G C Panzica
Journal:  J Neuroendocrinol       Date:  2012-01       Impact factor: 3.627

3.  Female reproductive status and circulating blood leukocyte expression of selected metabolic or signaling genes involved in sex steroid metabolism.

Authors:  Janet R Osuch; Wei-Wen Hsu; David Todem; Jeffrey Landgraf; Dorota Mikucki; Pam S Haan; Wilfried Karmaus
Journal:  Int J Mol Epidemiol Genet       Date:  2012-05-15

Review 4.  [Gender differences in acute and chronic pain conditions. Implications for diagnosis and therapy].

Authors:  M Schopper; J Fleckenstein; D Irnich
Journal:  Schmerz       Date:  2013-09       Impact factor: 1.107

5.  Effects of bisphenol A and triclocarban on brain-specific expression of aromatase in early zebrafish embryos.

Authors:  Eunah Chung; Maria C Genco; Laura Megrelis; Joan V Ruderman
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-17       Impact factor: 11.205

Review 6.  Insights into rapid modulation of neuroplasticity by brain estrogens.

Authors:  Deepak P Srivastava; Kevin M Woolfrey; Peter Penzes
Journal:  Pharmacol Rev       Date:  2013-09-27       Impact factor: 25.468

Review 7.  On the role of brain aromatase in females: why are estrogens produced locally when they are available systemically?

Authors:  Charlotte A Cornil
Journal:  J Comp Physiol A Neuroethol Sens Neural Behav Physiol       Date:  2017-10-30       Impact factor: 1.836

Review 8.  Development of subtype-selective oestrogen receptor-based therapeutics.

Authors:  Stefan Nilsson; Konrad F Koehler; Jan-Åke Gustafsson
Journal:  Nat Rev Drug Discov       Date:  2011-09-16       Impact factor: 84.694

Review 9.  L-Type Calcium Channels Modulation by Estradiol.

Authors:  Nelson E Vega-Vela; Daniel Osorio; Marco Avila-Rodriguez; Janneth Gonzalez; Luis Miguel García-Segura; Valentina Echeverria; George E Barreto
Journal:  Mol Neurobiol       Date:  2016-08-15       Impact factor: 5.590

10.  Site-specific effects of aromatase inhibition on the activation of male sexual behavior in male Japanese quail (Coturnix japonica).

Authors:  Marie-Pierre de Bournonville; Laura M Vandries; Gregory F Ball; Jacques Balthazart; Charlotte A Cornil
Journal:  Horm Behav       Date:  2019-01-09       Impact factor: 3.587
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