Literature DB >> 20476876

Successful treatment of hereditary factor VII deficiency presented for the first time with epistaxis in pregnancy: a case report.

Gülşah Aynaoğlu1, Gülşen Doğan Durdağ, Batuhan Ozmen, Feride Söylemez.   

Abstract

OBJECTIVE: To present a rare case with factor VII deficiency (FVIID) that first diagnosed during pregnancy, and to disccuss the ante-, peri- and postpartum management. STUDY
DESIGN: A case report and review of the literature.
RESULTS: FVIID was diagnosed for the first time in a 23-year-old pregnant woman at the 24th week of gestation due to complaint of intermittent epistaxis. She was successfully treated by ante-, peripartum and postpartum replacement of recombinant FVII (rFVII). She was uneventfully discharged on the 3rd postoperative day and referred to hematology department for further follow-up.
CONCLUSION: FVIID, a rare cause of ante- and postpartum hemorrhages that may differently present by other hemorrhages (i.e.: epistaxis), can be optimally managed with replacement of rFVII.

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Year:  2010        PMID: 20476876     DOI: 10.3109/14767050903440463

Source DB:  PubMed          Journal:  J Matern Fetal Neonatal Med        ISSN: 1476-4954


  2 in total

Review 1.  Is prophylaxis required for delivery in women with factor VII deficiency?

Authors:  L M Baumann Kreuziger; Colleen T Morton; Mark T Reding
Journal:  Haemophilia       Date:  2013-04-22       Impact factor: 4.287

2.  Management of Severe Epistaxis during Pregnancy: A Case Report and Review of the Literature.

Authors:  Maria Grazia Piccioni; Martina Derme; Laura Salerno; Elisa Morrocchi; Francesco Pecorini; Maria Grazia Porpora; Roberto Brunelli
Journal:  Case Rep Obstet Gynecol       Date:  2019-01-20
  2 in total

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