Literature DB >> 20476748

Alkaloids from the bark of Guatteria hispida and their evaluation as antioxidant and antimicrobial agents.

Emmanoel Vilaça Costa1, Maria Lúcia B Pinheiro, Andersson Barison, Francinete R Campos, Marcos J Salvador, Beatriz Helena L N S Maia, Elaine C Cabral, Marcos N Eberlin.   

Abstract

Phytochemical investigation of the bark of Guatteria hispida afforded three new alkaloids, 9-methoxy-O-methylmoschatoline (1), 9-methoxyisomoschatoline (2), and isocerasonine (3), along with 10 known alkaloids, 8-oxopseudopalmatine (4), O-methylmoschatoline (5), lysicamine (6), liriodenine (7), 10-methoxyliriodenine (8), nornuciferine (9), anonaine (10), xylopine (11), coreximine (12), and isocoreximine (13). The major compounds, 2, 6, 12, and 13, showed significant antioxidant capacity in the ORAC(FL) assay. Compounds 5, 6, and 7 were active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1).

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20476748     DOI： 10.1021/np100013r

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Treatment with aqueous extract from Croton cajucara Benth reduces hepatic oxidative stress in streptozotocin-diabetic rats.

Authors:  Graziella Ramos Rodrigues; Fábio Cangeri Di Naso; Marilene Porawski; Eder Marcolin; Nélson Alexandre Kretzmann; Alexandre de Barros Falcão Ferraz; Marc Francois Richter; Cláudio Augusto Marroni; Norma Possa Marroni
Journal:  J Biomed Biotechnol       Date:  2012-07-02

2.  Synthesis, Characterization, and Bioactivity of Schiff Bases and Their Cd(2+), Zn(2+), Cu(2+), and Ni(2+) Complexes Derived from Chloroacetophenone Isomers with S-Benzyldithiocarbazate and the X-Ray Crystal Structure of S-Benzyl- β -N-(4-chlorophenyl)methylenedithiocarbazate.

Authors:  Mohammed Khaled Bin Break; M Ibrahim M Tahir; Karen A Crouse; Teng-Jin Khoo
Journal:  Bioinorg Chem Appl       Date:  2013-11-11       Impact factor: 7.778

3.  Simultaneous Determination of Five Alkaloids by HPLC-MS/MS Combined With Micro-SPE in Rat Plasma and Its Application to Pharmacokinetics After Oral Administration of Lotus Leaf Extract.

Authors:  Shuhan Zou; Yuanyuan Ge; Xuanhao Chen; Jin Li; Xuejing Yang; Hui Wang; Xiumei Gao; Yan-Xu Chang
Journal:  Front Pharmacol       Date:  2019-10-22       Impact factor: 5.810

4.  Novel total syntheses of oxoaporphine alkaloids enabled by mild Cu-catalyzed tandem oxidation/aromatization of 1-Bn-DHIQs.

Authors:  Bo Zheng; Hui-Ya Qu; Tian-Zhuo Meng; Xia Lu; Jie Zheng; Yun-Gang He; Qi-Qi Fan; Xiao-Xin Shi
Journal:  RSC Adv       Date:  2018-08-14       Impact factor: 4.036

5.  Role of the phloem in the biochemistry and ecophysiology of benzylisoquinoline alkaloid metabolism.

Authors:  Eun-Jeong Lee; Jillian M Hagel; Peter J Facchini
Journal:  Front Plant Sci       Date:  2013-06-11       Impact factor: 5.753

6.  Inverting the regioselectivity of the berberine bridge enzyme by employing customized fluorine-containing substrates.

Authors:  Verena Resch; Horst Lechner; Joerg H Schrittwieser; Silvia Wallner; Karl Gruber; Peter Macheroux; Wolfgang Kroutil
Journal:  Chemistry       Date:  2012-09-07       Impact factor: 5.236
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.