| Literature DB >> 2047574 |
G Pierrefiche1, G Topall, I Henriet, H Laborit.
Abstract
Gamma-hydroxybutyrate (GHB) administered to mice prior to alloxan antagonizes its diabetogenic action in a dose dependent fashion and up to 96 hours after injection. Results are discussed on the basis of free radical formation by alloxan and of the metabolic property of GHB which is known to increase the rate of operation of the pentose phosphate pathway.Entities:
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Year: 1991 PMID： 2047574
Source DB: PubMed Journal: Res Commun Chem Pathol Pharmacol ISSN： 0034-5164