Literature DB >> 2047362

Protection against gastric ulcer by verapamil.

S K Srivastava1, C Nath, M B Gupta, S Vrat, J N Sinha, K N Dhawan, G P Gupta.   

Abstract

The effect of verapamil, a calcium channel blocker, was studied against stress (cold restraint), aspirin and pylorus ligation induced gastric ulcers in rats. Verapamil inhibited ulcerogenic response and ulcer index in all the three types of ulcers. Verapamil also decreased total and free gastric acidity without changing gastric secretory volume.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 2047362     DOI： 10.1016/s1043-6618(05)80109-4

Source DB:  PubMed          Journal:  Pharmacol Res        ISSN： 1043-6618            Impact factor:   7.658


  8 in total

1.  Gastroprotective effect of anti-cancer compound rohitukine: possible role of gastrin antagonism and H(+) K (+)-ATPase inhibition.

Authors:  Neetu Singh; Pratibha Singh; Shishir Shrivastva; Sunil Kumar Mishra; Vijai Lakshmi; Rolee Sharma; Gautam Palit
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2011-11-24       Impact factor: 3.000

2.  Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme.

Authors:  Nada H El-Dershaby; Soad A El-Hawash; Shaymaa E Kassab; Hoda G Dabees; Ahmed E Abdel Moneim; Ibrahim A Abdel Wahab; Mohammad M Abd-Alhaseeb; Mostafa M M El-Miligy
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.756

3.  Anti-ulcerogenic and in vitro antioxidant activities of Lagenaria breviflora (LB) whole fruit ethanolic extract in laboratory animals.

Authors:  S A Onasanwo; Neetu Singh; A B Saba; A A Oyagbemi; O A Oridupa; Gautam Palit
Journal:  Pharmacognosy Res       Date:  2011-01

4.  Antiulcer effect of the methanolic extract of Tamarindus indica seeds in different experimental models.

Authors:  Pankaj Kalra; Sunil Sharma; Suresh Kumar
Journal:  J Pharm Bioallied Sci       Date:  2011-04

5.  Anti-ulcer and ulcer healing potentials of Musa sapientum peel extract in the laboratory rodents.

Authors:  Samuel Adetunji Onasanwo; Benjamin Obukowho Emikpe; Austin Azubuike Ajah; Taiwo Olayemi Elufioye
Journal:  Pharmacognosy Res       Date:  2013-07

6.  A new gastroprotective effect of limonoid compounds xyloccensins x and y from xylocarpus molluccensis in rats.

Authors:  Vijai Lakshmi; Vaibhav Mishra; Gautam Palit
Journal:  Nat Prod Bioprospect       Date:  2014-08-03

7.  Isolation, characterization, and in silico, in vitro and in vivo antiulcer studies of isoimperatorin crystallized from Ostericum koreanum.

Authors:  Hussain Raza; Qamar Abbas; Mubashir Hassan; Seong-Hui Eo; Zaman Ashraf; Daeyoung Kim; Abdul Rehman Phull; Song Ja Kim; Sung Kwon Kang; Sung-Yum Seo
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

8.  Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones.

Authors:  Perihan A Elzahhar; Rana A Alaaeddine; Rasha Nassra; Azza Ismail; Hala F Labib; Mohamed G Temraz; Ahmed S F Belal; Ahmed F El-Yazbi
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.