Literature DB >> 20473566

Comparison of endoscopy, histology, and cytokine mRNA of the equine gastric mucosa.

M Pietra1, M Morini, G Perfetti, A Spadari, P Vigo, A Peli.   

Abstract

In recent years, gastric ulceration has been recognized as a common, possibly performance-limiting disease, of adult horses. The aim of this study was to compare endoscopic features, histological diagnosis, and mRNA levels of various cytokines (TNF-alpha, IL-1beta, and IL-13) from horse gastric biopsies. Eleven horses suffering from equine gastric ulcer syndrome and seven horses with normal histological gastric features were assessed. No correlation between endoscopic features and histology (i.e., the gold standard) was observed. Based on histological diagnosis, a significant (p < 0.05) increase in cytokine mRNA levels (specifically, TNF-alpha and IL-13) was observed in horses affected by equine ulcerative gastric syndrome.

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Year:  2010        PMID： 20473566     DOI： 10.1007/s11259-010-9401-6

Source DB:  PubMed          Journal:  Vet Res Commun        ISSN： 0165-7380            Impact factor:   2.459


  7 in total

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Journal:  Vet Res Commun       Date:  2008-09       Impact factor: 2.459

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3.  Development of a microarray for studying porcine cytokine production in blood mononuclear cells and intestinal biopsies.

Authors:  M Andersson; M Berg; C Fossum; M Jensen-Waern
Journal:  J Vet Med A Physiol Pathol Clin Med       Date:  2007-04

Review 4.  Equine gastric ulcer syndrome in adult horses: a review.

Authors:  R J W Bell; T D Mogg; J K Kingston
Journal:  N Z Vet J       Date:  2007-02       Impact factor: 1.628

5.  The prevalence and distribution of gastric ulceration in 345 racehorses.

Authors:  L M Begg; C B O'Sullivan
Journal:  Aust Vet J       Date:  2003-04       Impact factor: 1.281

6.  The relationship of mucosal bacteria to duodenal histopathology, cytokine mRNA, and clinical disease activity in cats with inflammatory bowel disease.

Authors:  S Janeczko; D Atwater; E Bogel; A Greiter-Wilke; A Gerold; M Baumgart; H Bender; P L McDonough; S P McDonough; R E Goldstein; K W Simpson
Journal:  Vet Microbiol       Date:  2007-10-22       Impact factor: 3.293

7.  Epithelial expression of mRNA and protein for IL-6, IL-10 and TNF-alpha in endobronchial biopsies in horses with recurrent airway obstruction.

Authors:  Miia Riihimäki; Amanda Raine; Jamshid Pourazar; Thomas Sandström; Tatiana Art; Pierre Lekeux; Laurent Couëtil; John Pringle
Journal:  BMC Vet Res       Date:  2008-02-23       Impact factor: 2.741
  7 in total
  2 in total

1.  Comparison of commercial RNA extraction kits and qPCR master mixes for studying gene expression in small biopsy tissue samples from the equine gastric epithelium.

Authors:  Parichart Tesena; Wasamon Korchunjit; Jane Taylor; Tuempong Wongtawan
Journal:  J Equine Sci       Date:  2017-12-16

2.  Diagnostic accuracy of blood sucrose as a screening test for equine gastric ulcer syndrome (EGUS) in adult horses.

Authors:  Michael Hewetson; Ben William Sykes; Gayle Davina Hallowell; Riitta-Mari Tulamo
Journal:  Acta Vet Scand       Date:  2017-03-11       Impact factor: 1.695
  2 in total

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