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Literature DB >> 20473533

Inflammation processes in perinatal brain damage.

Vincent Degos¹, Géraldine Favrais, Angela M Kaindl, Stéphane Peineau, Anne Marie Guerrot, Catherine Verney, Pierre Gressens.

Abstract

Once viewed as an isolated, immune-privileged organ, the central nervous system has undergone a conceptual change. Neuroinflammation has moved into the focus of research work regarding pathomechanisms underlying perinatal brain damage. In this review, we provide an overview of current concepts regarding perinatal brain damage and the role of inflammation in the disease pathomechanism.

Entities: Disease

Mesh：

Year: 2010 PMID： 20473533 DOI： 10.1007/s00702-010-0411-x

Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN： 0300-9564 Impact factor: 3.575

89 in total

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6. Effects of interleukin-10 on neonatal excitotoxic brain lesions in mice.

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7. Interleukin-18 involvement in hypoxic-ischemic brain injury.

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8. Maternal exposure to LPS induces hypomyelination in the internal capsule and programmed cell death in the deep gray matter in newborn rats.

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9. Low endogenous G-protein-coupled receptor kinase 2 sensitizes the immature brain to hypoxia-ischemia-induced gray and white matter damage.

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10. Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate.

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Review 2. Neuroinflammation: beneficial and detrimental effects after traumatic brain injury.

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3. Neonatal exposure to lipopolysaccharide enhances vulnerability of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life.

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5. Circulating Inflammatory-Associated Proteins in the First Month of Life and Cognitive Impairment at Age 10 Years in Children Born Extremely Preterm.

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6. G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration.

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7. Neonatal systemic exposure to lipopolysaccharide enhances susceptibility of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life.

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8. Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: a preliminary report.

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Review 9. Corticosteroids and perinatal hypoxic-ischemic brain injury.

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10. Detection of cerebral spinal fluid-associated chemokines in birth traumatized premature babies by chip-based immunoaffinity CE.

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