Literature DB >> 20472747

Family history, near work, outdoor activity, and myopia in Singapore Chinese preschool children.

Wilson Low1, Mohamed Dirani, Gus Gazzard, Yiong-Huak Chan, Hui-Jun Zhou, Prabakaran Selvaraj, Kah-Guan Au Eong, Terri L Young, Paul Mitchell, Tien-Yin Wong, Seang-Mei Saw.   

Abstract

AIMS: To investigate the risk factors for myopia, including near work and outdoor activity, in Singapore Chinese preschool children.
METHODS: A cross-sectional study, with disproportionate random sampling by 6-month age groups, of 3009 Singapore Chinese children aged 6-72 months was performed. Information on family history, near work and outdoor activity was obtained. Spherical equivalent refraction (SER) was assessed.
RESULTS: Children with two myopic parents were more likely to be myopic (adjusted OR=1.91; 95% CI 1.38 to 2.63) and to have a more myopic SER (regression coefficient=-0.35; 95% CI -0.47 to -0.22) than children without myopic parents. For each 1 cm taller height, the SER was more myopic by 0.01 dioptres. Neither near work nor outdoor activity was associated with preschool myopia.
CONCLUSIONS: A family history of myopia was the strongest factor associated with preschool myopia. In contrast, neither near work nor outdoor activity was found to be associated with early myopia. These data suggest that genetic factors may play a more substantial role in the development of early-onset myopia than key environmental factors.

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Year:  2010        PMID: 20472747      PMCID: PMC4041336          DOI: 10.1136/bjo.2009.173187

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  25 in total

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2.  Nearwork in early-onset myopia.

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6.  Cross-sectional study of near-work and myopia in kindergarten children in Singapore.

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Authors:  Donald O Mutti; G Lynn Mitchell; Melvin L Moeschberger; Lisa A Jones; Karla Zadnik
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8.  Outdoor activity and myopia in Singapore teenage children.

Authors:  M Dirani; L Tong; G Gazzard; X Zhang; A Chia; T L Young; K A Rose; P Mitchell; S-M Saw
Journal:  Br J Ophthalmol       Date:  2009-02-11       Impact factor: 4.638

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  59 in total

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Review 9.  Pharmacology of myopia and potential role for intrinsic retinal circadian rhythms.

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Journal:  Exp Eye Res       Date:  2013-01-08       Impact factor: 3.467

10.  Association of Parental Myopia With Higher Risk of Myopia Among Multiethnic Children Before School Age.

Authors:  Xuejuan Jiang; Kristina Tarczy-Hornoch; Susan A Cotter; Saiko Matsumura; Paul Mitchell; Kathryn A Rose; Joanne Katz; Seang-Mei Saw; Rohit Varma
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