Literature DB >> 20471282

Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice.

Sang-Yun Lee1, Jason Stadanlick, Dietmar J Kappes, David L Wiest.   

Abstract

While insights into the molecular processes that specify adoption of the alphabeta and gammadelta fates are beginning to emerge, the basis for control of specification remains highly controversial. This review highlights the current models attempting to explain T lineage commitment. Recent observations support the hypothesis that the T cell receptor (TCR) provides instructive cues through differences in TCR signaling intensity and/or longevity. Accordingly, we review evidence addressing the importance of differences in signal strength/longevity, how signals differing in intensity/longevity may be generated, and finally how such signals modulate the activity of downstream effectors to promote the opposing developmental fates. 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20471282      PMCID： PMC2906684          DOI： 10.1016/j.smim.2010.04.008

Source DB:  PubMed          Journal:  Semin Immunol        ISSN： 1044-5323            Impact factor:   11.130


  142 in total

Review 1.  Signals involved in gamma/delta T cell versus alpha/beta T cell lineage commitment.

Authors:  A C Hayday; D F Barber; N Douglas; E S Hoffman
Journal:  Semin Immunol       Date:  1999-08       Impact factor: 11.130

Review 2.  [gamma][delta] cells: a right time and a right place for a conserved third way of protection.

Authors:  A C Hayday
Journal:  Annu Rev Immunol       Date:  2000       Impact factor: 28.527

3.  Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3.

Authors:  R R Rivera; C P Johns; J Quan; R S Johnson; C Murre
Journal:  Immunity       Date:  2000-01       Impact factor: 31.745

4.  Cutting edge: protective response to pulmonary injury requires gamma delta T lymphocytes.

Authors:  D P King; D M Hyde; K A Jackson; D M Novosad; T N Ellis; L Putney; M Y Stovall; L S Van Winkle; B L Beaman; D A Ferrick
Journal:  J Immunol       Date:  1999-05-01       Impact factor: 5.422

5.  Characterization of TCR gene rearrangements during adult murine T cell development.

Authors:  F Livák; M Tourigny; D G Schatz; H T Petrie
Journal:  J Immunol       Date:  1999-03-01       Impact factor: 5.422

6.  Essential role of LAT in T cell development.

Authors:  W Zhang; C L Sommers; D N Burshtyn; C C Stebbins; J B DeJarnette; R P Trible; A Grinberg; H C Tsay; H M Jacobs; C M Kessler; E O Long; P E Love; L E Samelson
Journal:  Immunity       Date:  1999-03       Impact factor: 31.745

7.  Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors.

Authors:  B Blom; M H Heemskerk; M C Verschuren; J J van Dongen; A P Stegmann; A Q Bakker; F Couwenberg; P C Res; H Spits
Journal:  EMBO J       Date:  1999-05-17       Impact factor: 11.598

Review 8.  Control of early thymocyte development by the pre-T cell receptor complex: A receptor without a ligand?

Authors:  D L Wiest; M A Berger; M Carleton
Journal:  Semin Immunol       Date:  1999-08       Impact factor: 11.130

9.  A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis.

Authors:  R Barndt; M F Dai; Y Zhuang
Journal:  J Immunol       Date:  1999-09-15       Impact factor: 5.422

10.  Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes.

Authors:  J Kang; M Coles; D H Raulet
Journal:  J Exp Med       Date:  1999-10-04       Impact factor: 14.307
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  14 in total

1.  Combined deletion of Id2 and Id3 genes reveals multiple roles for E proteins in invariant NKT cell development and expansion.

Authors:  Jia Li; Di Wu; Ning Jiang; Yuan Zhuang
Journal:  J Immunol       Date:  2013-10-11       Impact factor: 5.422

2.  Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development.

Authors:  Juliette Roels; Anna Kuchmiy; Matthias De Decker; Steven Strubbe; Marieke Lavaert; Kai Ling Liang; Georges Leclercq; Bart Vandekerckhove; Filip Van Nieuwerburgh; Pieter Van Vlierberghe; Tom Taghon
Journal:  Nat Immunol       Date:  2020-07-27       Impact factor: 25.606

3.  Rpl22 Loss Selectively Impairs αβ T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling.

Authors:  Nehal R Solanki; Jason E Stadanlick; Yong Zhang; Ann-Cecile Duc; Sang-Yun Lee; Jens Peter Holst Lauritsen; Zhiqiang Zhang; David L Wiest
Journal:  J Immunol       Date:  2016-08-03       Impact factor: 5.422

4.  Noncanonical mode of ERK action controls alternative αβ and γδ T cell lineage fates.

Authors:  Sang-Yun Lee; Francis Coffey; Shawn P Fahl; Suraj Peri; Michele Rhodes; Kathy Q Cai; Michael Carleton; Stephen M Hedrick; Hans Joerg Fehling; Juan Carlos Zúñiga-Pflücker; Dietmar J Kappes; David L Wiest
Journal:  Immunity       Date:  2014-11-28       Impact factor: 31.745

Review 5.  αβ versus γδ fate choice: counting the T-cell lineages at the branch point.

Authors:  Taras Kreslavsky; Michael Gleimer; Annette I Garbe; Harald von Boehmer
Journal:  Immunol Rev       Date:  2010-11       Impact factor: 12.988

6.  Control of hematopoietic stem cell emergence by antagonistic functions of ribosomal protein paralogs.

Authors:  Yong Zhang; Anne-Cécile E Duc; Shuyun Rao; Xiao-Li Sun; Alison N Bilbee; Michele Rhodes; Qin Li; Dietmar J Kappes; Jennifer Rhodes; David L Wiest
Journal:  Dev Cell       Date:  2013-02-25       Impact factor: 12.270

7.  A novel T cell subset with trans-rearranged Vγ-Cβ TCRs shows Vβ expression is dispensable for lineage choice and MHC restriction.

Authors:  Steven Bowen; Peter Sun; Ferenc Livak; Susan Sharrow; Richard J Hodes
Journal:  J Immunol       Date:  2013-12-04       Impact factor: 5.422

8.  Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development.

Authors:  Kaat Durinck; Marieke Lavaert; Joni Van der Meulen; Anne-Catherine Dolens; Imke Velghe; Jelle De Medts; Karin Weening; Juliette Roels; Katrien De Mulder; Pieter-Jan Volders; Katleen De Preter; Tessa Kerre; Bart Vandekerckhove; Georges Leclercq; Jo Vandesompele; Pieter Mestdagh; Pieter Van Vlierberghe; Frank Speleman; Tom Taghon
Journal:  EMBO Rep       Date:  2020-04-07       Impact factor: 8.807

9.  The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.

Authors:  Masaki Miyazaki; Richard R Rivera; Kazuko Miyazaki; Yin C Lin; Yasutoshi Agata; Cornelis Murre
Journal:  Nat Immunol       Date:  2011-08-21       Impact factor: 25.606

10.  In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis.

Authors:  Hervé Luche; Tata Nageswara Rao; Suresh Kumar; Alpaslan Tasdogan; Franziska Beckel; Carmen Blum; Vera C Martins; Hans-Reimer Rodewald; Hans Jörg Fehling
Journal:  J Exp Med       Date:  2013-03-18       Impact factor: 14.307
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