Literature DB >> 2046943

Cytotoxic activity in plasma from patients with amyotrophic lateral sclerosis.

K Overgaard1, L Werdelin, H Sørensen, P Mogensen, G Boysen.   

Abstract

The present study evaluates an assay of cytotoxic effect of plasma from patients with amyotrophic lateral sclerosis. Plasma from 20 recently diagnosed ALS patients induced hemolysis of normal red blood cells with a significantly greater intensity than that of normal controls. After at least 1 month of treatment with prednisone and azathioprine, the hemolytic activity of ALS plasma was reduced but was still higher than that of control plasma.

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Year:  1991        PMID: 2046943     DOI: 10.1212/wnl.41.6.925

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  1 in total

1.  Amyotrophic lateral sclerosis and the innate immune system: protocol for establishing a biobank and statistical analysis plan.

Authors:  Anne-Lene Kjældgaard; Katrine Pilely; Karsten Skovgaard Olsen; Anne Øberg Lauritsen; Stephen Wørlich Pedersen; Kirsten Møller; Peter Garred
Journal:  BMJ Open       Date:  2020-08-05       Impact factor: 2.692

  1 in total

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