Literature DB >> 2046886

Opposite action of oxytocin and its peptide antagonists on social memory in rats.

P Popik1, J Vetulani.   

Abstract

The synthetic 1-beta,beta-disubstituted analogues of [1-deamino]-oxytocin, [1'-(1'-thio-4'-methylcyclohexane)-acetic acid 1]-oxytocin (MeCAOT) a peripheral oxytocin antagonist, and [1'-(1'-methyl-4'-thiopiperidine)-acetic acid 1]-oxytocin (MePAOT), devoid of peripheral anti-oxytocin activity, were found to improve social memory of rats. The social memory in rats was disrupted by a wide range of doses of oxytocin (6-750 mU/kg) and this amnestic effect of oxytocin was antagonised by MePAOT and MeCAOT.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 2046886     DOI： 10.1016/0143-4179(91)90159-g

Source DB:  PubMed          Journal:  Neuropeptides        ISSN： 0143-4179            Impact factor:   3.286


  15 in total

1.  Evidence for a role of oxytocin receptors in the long-term establishment of dominance hierarchies.

Authors:  Marjan Timmer; M Isabel Cordero; Yannick Sevelinges; Carmen Sandi
Journal:  Neuropsychopharmacology       Date:  2011-07-13       Impact factor: 7.853

2.  Maternal contact differentially modulates central and peripheral oxytocin in rat pups during a brief regime of mother-pup interaction that induces a filial huddling preference.

Authors:  S Kojima; R A Stewart; G E Demas; J R Alberts
Journal:  J Neuroendocrinol       Date:  2012-05       Impact factor: 3.627

3.  Antiaggressive activity of central oxytocin in male rats.

Authors:  Federica Calcagnoli; Sietse F de Boer; Monika Althaus; Johan A den Boer; Jaap M Koolhaas
Journal:  Psychopharmacology (Berl)       Date:  2013-04-28       Impact factor: 4.530

4.  Prenatal stress produces social behavior deficits and alters the number of oxytocin and vasopressin neurons in adult rats.

Authors:  Marcelo Alves de Souza; Lígia Aline Centenaro; Pâmela Rossi Menegotto; Thiago Pereira Henriques; Juliana Bonini; Matilde Achaval; Aldo Bolten Lucion
Journal:  Neurochem Res       Date:  2013-04-30       Impact factor: 3.996

5.  Role of oxytocin receptors in modulation of fear by social memory.

Authors:  Yomayra F Guzmán; Natalie C Tronson; Keisuke Sato; Ivana Mesic; Anita L Guedea; Katsuhiko Nishimori; Jelena Radulovic
Journal:  Psychopharmacology (Berl)       Date:  2013-11-28       Impact factor: 4.530

6.  WAY 267,464, a non-peptide oxytocin receptor agonist, impairs social recognition memory in rats through a vasopressin 1A receptor antagonist action.

Authors:  Callum Hicks; Linnet Ramos; Tristan A Reekie; Rajeshwar Narlawar; Michael Kassiou; Iain S McGregor
Journal:  Psychopharmacology (Berl)       Date:  2015-03-13       Impact factor: 4.530

7.  Housing conditions and stimulus females: a robust social discrimination task for studying male rodent social recognition.

Authors:  Abbe H Macbeth; Jennifer Stepp Edds; W Scott Young
Journal:  Nat Protoc       Date:  2009-10-08       Impact factor: 13.491

8.  Low doses of oxytocin facilitate social recognition in rats.

Authors:  P Popik; J Vetulani; J M van Ree
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

9.  Kynurenic acid and 5,7-dichlorokynurenic acids improve social and object recognition in male rats.

Authors:  Z Hlinák; I Krejci
Journal:  Psychopharmacology (Berl)       Date:  1995-08       Impact factor: 4.530

10.  Involvement of the oxytocin system in the bed nucleus of the stria terminalis in the sex-specific regulation of social recognition.

Authors:  Kelly M Dumais; Andrea G Alonso; Marisa A Immormino; Remco Bredewold; Alexa H Veenema
Journal:  Psychoneuroendocrinology       Date:  2015-11-17       Impact factor: 4.905
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.