BACKGROUND: Community-acquired Staphylococcus aureus (CA-SA) infections are common among pediatric patients in Hawaii. OBJECTIVE: We wanted to characterize the radiological features of methicillin-susceptible (CA-MSSA) and methicillin-resistant (CA-MRSA) staphylococcal pneumonia in Hawaiian children. MATERIALS AND METHODS: We retrospectively reviewed medical records and imaging studies of children with SA pneumonia identified from 1996 through 2007. RESULTS: Of 40 children, 26 (65%) had CA-MRSA pneumonia and 14 patients (35%) had CA-MSSA pneumonia. CA-MRSA patients were significantly younger than CA-MSSA patients (65% younger than 1 year vs. 36% older). In a majority (62%) of CA-MRSA patients, the consolidation was unilateral; in most of the CA-MSSA cases (79%), the consolidation was bilateral. Fifty percent of the patients with CA-MRSA and 21% of those with CA-MSSA had pneumatoceles (P = 0.1). CA-MRSA patients more commonly had pleural effusions (85% vs. 64% for CA-MSSA) and pleural thickening (50% vs. 36% for CA-MSSA). CONCLUSION: This case series describes the radiologic characteristics of CA-MRSA and CA-MSSA pneumonia in children in a highly endemic area. We found that CA-MRSA pneumonias are unilateral in a majority of pediatric pneumonia cases, are more common in children 1 year or younger, and have higher rates of complications in comparison to CA-MSSA patients.
BACKGROUND: Community-acquired Staphylococcus aureus (CA-SA) infections are common among pediatric patients in Hawaii. OBJECTIVE: We wanted to characterize the radiological features of methicillin-susceptible (CA-MSSA) and methicillin-resistant (CA-MRSA) staphylococcal pneumonia in Hawaiian children. MATERIALS AND METHODS: We retrospectively reviewed medical records and imaging studies of children with SA pneumonia identified from 1996 through 2007. RESULTS: Of 40 children, 26 (65%) had CA-MRSA pneumonia and 14 patients (35%) had CA-MSSA pneumonia. CA-MRSA patients were significantly younger than CA-MSSA patients (65% younger than 1 year vs. 36% older). In a majority (62%) of CA-MRSA patients, the consolidation was unilateral; in most of the CA-MSSA cases (79%), the consolidation was bilateral. Fifty percent of the patients with CA-MRSA and 21% of those with CA-MSSA had pneumatoceles (P = 0.1). CA-MRSA patients more commonly had pleural effusions (85% vs. 64% for CA-MSSA) and pleural thickening (50% vs. 36% for CA-MSSA). CONCLUSION: This case series describes the radiologic characteristics of CA-MRSA and CA-MSSA pneumonia in children in a highly endemic area. We found that CA-MRSA pneumonias are unilateral in a majority of pediatric pneumonia cases, are more common in children 1 year or younger, and have higher rates of complications in comparison to CA-MSSA patients.
Authors: John S Francis; Meg C Doherty; Uri Lopatin; Cecilia P Johnston; Gita Sinha; Tracy Ross; Mian Cai; Nadia N Hansel; Trish Perl; John R Ticehurst; Karen Carroll; David L Thomas; Eric Nuermberger; John G Bartlett Journal: Clin Infect Dis Date: 2004-12-07 Impact factor: 9.079
Authors: B C Herold; L C Immergluck; M C Maranan; D S Lauderdale; R E Gaskin; S Boyle-Vavra; C D Leitch; R S Daum Journal: JAMA Date: 1998-02-25 Impact factor: 56.272
Authors: Concepcion F Estivariz; Sarah Y Park; Jeffrey C Hageman; Jeffrey Dvorin; Marian M Melish; Rose Arpon; Pat Coon; Susan Slavish; Mary Kim; Linda K McDougal; Bette Jensen; Sigrid McAllister; David Lonsway; George Killgore; Paul E Effler; Daniel B Jernigan Journal: J Infect Date: 2006-09-20 Impact factor: 6.072
Authors: Simone Shurland; Min Zhan; Douglas D Bradham; Mary-Claire Roghmann Journal: Infect Control Hosp Epidemiol Date: 2007-02-15 Impact factor: 3.254
Authors: Juliane Bubeck Wardenburg; Amy M Palazzolo-Ballance; Michael Otto; Olaf Schneewind; Frank R DeLeo Journal: J Infect Dis Date: 2008-10-15 Impact factor: 5.226
Authors: Jeffrey C Hageman; Timothy M Uyeki; John S Francis; Daniel B Jernigan; J Gary Wheeler; Carolyn B Bridges; Stephen J Barenkamp; Dawn M Sievert; Arjun Srinivasan; Meg C Doherty; Linda K McDougal; George E Killgore; Uri A Lopatin; Rebecca Coffman; J Kathryn MacDonald; Sigrid K McAllister; Gregory E Fosheim; Jean B Patel; L Clifford McDonald Journal: Emerg Infect Dis Date: 2006-06 Impact factor: 6.883
Authors: Nishant Gupta; Robert Vassallo; Kathryn A Wikenheiser-Brokamp; Francis X McCormack Journal: Am J Respir Crit Care Med Date: 2015-06-15 Impact factor: 21.405