Literature DB >> 2046772

[Intestinal obstruction caused by non-absorbable tablets and Budd-Chiari syndrome in a patient with Crohn's disease].

B J Witteman1, I T Weterman, G Griffioen, C B Lamers.   

Abstract

Crohn's disease is a chronic inflammatory granulomatous disorder affecting any part of the gastrointestinal tract, particularly the terminal ileum and the colon. Familiar complications are strictures, fistulae, perforation, haemorrhages and malabsorption due to multiple resections. A patient with two rare complications of Crohn's disease is described. A 16-year-old female with ileocaecal Crohn's disease presented with anaemia and ileus. This ileus was caused by some 40 tablets of ferrosulphate with a non-soluble matrix, in the presence of an existing stenosis of the ileum due to Crohn's disease. An ileocaecal resection was performed. During an exacerbation of Crohn's disease she developed hepatic vein thrombosis with a Budd-Chiari syndrome (upper abdominal pain, hepatomegaly and ascites). Prescription of tablets with a non-soluble matrix is contraindicated in patients with a partial stenosis of the intestine. Patients with active Crohn's disease are predisposed to thromboembolic complications. Hepatic vein thrombosis in our patient may have been the result of hypercoagulability during the exacerbation of her disease.

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Year:  1991        PMID: 2046772

Source DB:  PubMed          Journal:  Ned Tijdschr Geneeskd        ISSN: 0028-2162


  4 in total

1.  Iatrogenic ileal obstruction in a patient with Crohn's disease.

Authors:  Luca P Piodi; Fabio M Ulivieri; Marina Carini; Angela Piccoli; Maria Teresa Bardella
Journal:  Dig Dis Sci       Date:  2004-08       Impact factor: 3.199

2.  Gastrointestinal safety of an extended-release, nondeformable, oral dosage form (OROS: a retrospective study.

Authors:  Dorsey M Bass; Mary Prevo; Deborah S Waxman
Journal:  Drug Saf       Date:  2002       Impact factor: 5.606

3.  Budd-Chiari syndrome in a patient with ulcerative colitis.

Authors:  Gopal Krishana Bohra; Vivek Chhabra; Naresh Midha; Binit Sureka
Journal:  BMJ Case Rep       Date:  2018-02-22

4.  Budd-Chiari syndrome: a rare and life-threatening complication of Crohn's disease.

Authors:  Camila C Simoes; Yezaz A Ghouri; Shehzad N Merwat; Heather L Stevenson
Journal:  BMJ Case Rep       Date:  2018-01-17
  4 in total

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