BACKGROUND: X-linked reticulate pigmentary disorder is a very rare cutaneous condition characterized by different clinical manifestations according to sex. METHODS: We report a 31-year-old woman with X-linked reticulate pigmentary disorder. RESULTS: On examination, there were multiple, asymptomatic, brownish macules in linear and whorled patterns over the trunk, axillae, groin, and extremities. The woman had not experienced any systemic manifestations involving the gastrointestinal, pulmonary, or ocular systems. Her hair, teeth, and nails were normal on close observation. All laboratory data were within the normal range. A genetic study was not performed. CONCLUSIONS: Although a genetic study was not performed, we believe that our patient can be diagnosed with X-linked reticulate pigmentary disorder according to the clinical and histopathologic findings.
BACKGROUND:X-linked reticulate pigmentary disorder is a very rare cutaneous condition characterized by different clinical manifestations according to sex. METHODS: We report a 31-year-old woman with X-linked reticulate pigmentary disorder. RESULTS: On examination, there were multiple, asymptomatic, brownish macules in linear and whorled patterns over the trunk, axillae, groin, and extremities. The woman had not experienced any systemic manifestations involving the gastrointestinal, pulmonary, or ocular systems. Her hair, teeth, and nails were normal on close observation. All laboratory data were within the normal range. A genetic study was not performed. CONCLUSIONS: Although a genetic study was not performed, we believe that our patient can be diagnosed with X-linked reticulate pigmentary disorder according to the clinical and histopathologic findings.
Authors: Petro Starokadomskyy; Terry Gemelli; Jonathan J Rios; Chao Xing; Richard C Wang; Haiying Li; Vladislav Pokatayev; Igor Dozmorov; Shaheen Khan; Naoteru Miyata; Guadalupe Fraile; Prithvi Raj; Zhe Xu; Zigang Xu; Lin Ma; Zhimiao Lin; Huijun Wang; Yong Yang; Dan Ben-Amitai; Naama Orenstein; Huda Mussaffi; Eulalia Baselga; Gianluca Tadini; Eyal Grunebaum; Adrijan Sarajlija; Konrad Krzewski; Edward K Wakeland; Nan Yan; Maria Teresa de la Morena; Andrew R Zinn; Ezra Burstein Journal: Nat Immunol Date: 2016-03-28 Impact factor: 25.606
Authors: Petro Starokadomskyy; Katelynn M Wilton; Konrad Krzewski; Adam Lopez; Luis Sifuentes-Dominguez; Brittany Overlee; Qing Chen; Ann Ray; Aleksandra Gil-Krzewska; Mary Peterson; Lisa N Kinch; Luis Rohena; Eyal Grunebaum; Andrew R Zinn; Nick V Grishin; Daniel D Billadeau; Ezra Burstein Journal: JCI Insight Date: 2019-11-01