BACKGROUND: While functioning ability, quality of life (QoL) and depression are widely studied phenomena in schizophrenia, little is known about functioning ability, QoL and depression, especially among adolescents at high risk of developing first-episode psychosis. AIM: To investigate associations between high risk of developing psychosis and functioning ability, depression and QoL among adolescents. METHODS: The data was collected by an early intervention team in Espoo, Finland, between 1 January 2007 and 31 May 2008. Subjects at high risk of developing psychosis were compared with subjects not at high risk in terms of functioning ability (GAF), QoL (16D) and depressive symptoms (RBDI) in a cross-sectional setting. The study was conducted with 80 adolescents (mean age 14.7, range 12-18 years). RESULTS: Those at high risk of developing psychosis had significantly lower and poorer scores in functioning ability (53.4 vs. 58.4, P=0.006), had higher and poorer scores in QoL (10.81 vs. 7.05, P=0.002) and higher and poorer scores in depression (8.95 vs. 4.76, P=0.001) than those who did not meet the criteria of being at high risk of developing psychosis. Poorer functioning ability independently explained being at high risk of developing psychosis at a statistically significant level (P=0.021) in a logistic regression analysis after age, gender, depression and QoL were adjusted for. CONCLUSIONS: Poor functioning ability seems to be associated with high risk of developing psychosis among adolescents.
BACKGROUND: While functioning ability, quality of life (QoL) and depression are widely studied phenomena in schizophrenia, little is known about functioning ability, QoL and depression, especially among adolescents at high risk of developing first-episode psychosis. AIM: To investigate associations between high risk of developing psychosis and functioning ability, depression and QoL among adolescents. METHODS: The data was collected by an early intervention team in Espoo, Finland, between 1 January 2007 and 31 May 2008. Subjects at high risk of developing psychosis were compared with subjects not at high risk in terms of functioning ability (GAF), QoL (16D) and depressive symptoms (RBDI) in a cross-sectional setting. The study was conducted with 80 adolescents (mean age 14.7, range 12-18 years). RESULTS: Those at high risk of developing psychosis had significantly lower and poorer scores in functioning ability (53.4 vs. 58.4, P=0.006), had higher and poorer scores in QoL (10.81 vs. 7.05, P=0.002) and higher and poorer scores in depression (8.95 vs. 4.76, P=0.001) than those who did not meet the criteria of being at high risk of developing psychosis. Poorer functioning ability independently explained being at high risk of developing psychosis at a statistically significant level (P=0.021) in a logistic regression analysis after age, gender, depression and QoL were adjusted for. CONCLUSIONS: Poor functioning ability seems to be associated with high risk of developing psychosis among adolescents.
Authors: Elizabeth C Thompson; Nicole D Andorko; Pamela Rakhshan Rouhakhtar; Zachary B Millman; Kristin Sagun; Susan C Han; Doha Chibani; Gloria M Reeves; Bruce Herman; Jason Schiffman Journal: J College Stud Psychother Date: 2020-09-04
Authors: Alexandros Georgiadis; Robbie Duschinsky; Jesus Perez; Peter B Jones; Debra Russo; Clare Knight; Emma Soneson; Mary Dixon-Woods Journal: BMJ Open Date: 2018-11-08 Impact factor: 2.692
Authors: Emma Soneson; Debra Russo; Clare Knight; Louise Lafortune; Margaret Heslin; Jan Stochl; Alex Georgiadis; Julieta Galante; Robbie Duschinsky; Nick Grey; Leticia Gonzalez-Blanco; Juliet Couche; Michelle Griffiths; Hannah Murray; Nesta Reeve; Joanne Hodgekins; Paul French; David Fowler; Sarah Byford; Mary Dixon-Woods; Peter B Jones; Jesus Perez Journal: Syst Rev Date: 2019-05-23
Authors: Émélie Rondeau; Leandra Desjardins; Caroline Laverdière; Daniel Sinnett; Élie Haddad; Serge Sultan Journal: Health Psychol Behav Med Date: 2021-07-06
Authors: Christy Hui; Carmen Morcillo; Debra A Russo; Jan Stochl; Gillian F Shelley; Michelle Painter; Peter B Jones; Jesus Perez Journal: Schizophr Res Date: 2013-06-14 Impact factor: 4.939
Authors: Emma Soneson; Debra Russo; Jan Stochl; Margaret Heslin; Julieta Galante; Clare Knight; Nick Grey; Joanne Hodgekins; Paul French; David Fowler; Louise Lafortune; Sarah Byford; Peter B Jones; Jesus Perez Journal: Aust N Z J Psychiatry Date: 2020-05-28 Impact factor: 5.744