Literature DB >> 2046474

Multiple populations of serotonin receptors may modulate the behavioral effects of serotonergic agents.

R A Glennon1, N A Darmani, B R Martin.   

Abstract

In order to establish a functional role for the various populations of serotonin (5-HT) receptors, behavioral studies have been conducted over the past decade with serotonergic agonists and antagonists. And, although there is reason to believe that certain behavioral effects may be mediated via particular populations of 5-HT receptors, evidence now suggests that some serotonin-mediated behaviors may be modulated by the interaction of serotonergic agents at multiple subtypes of 5-HT receptors. The generality of these effects, and the exact mechanism(s) by which they occur, have yet to be elucidated. Nevertheless, over the past year, results from several different laboratories provide a growing recognition of this novel phenomenon.

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Year:  1991        PMID: 2046474     DOI: 10.1016/0024-3205(91)90603-9

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  11 in total

1.  Locomotor-activated neurons of the cat. I. Serotonergic innervation and co-localization of 5-HT7, 5-HT2A, and 5-HT1A receptors in the thoraco-lumbar spinal cord.

Authors:  Brian R Noga; Dawn M G Johnson; Mirta I Riesgo; Alberto Pinzon
Journal:  J Neurophysiol       Date:  2009-07-01       Impact factor: 2.714

2.  Psychedelics and the human receptorome.

Authors:  Thomas S Ray
Journal:  PLoS One       Date:  2010-02-02       Impact factor: 3.240

Review 3.  5-HT receptors as targets for the development of novel anxiolytic drugs: models, mechanisms and future directions.

Authors:  J E Barrett; K E Vanover
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

Review 4.  Obsessive-compulsive disorder in schizophrenia: epidemiologic and biologic overlap.

Authors:  P Tibbo; L Warneke
Journal:  J Psychiatry Neurosci       Date:  1999-01       Impact factor: 6.186

5.  Possible antidepressant dihydroergosine preferentially binds to 5-HT1B receptor sites in the rat hippocampus.

Authors:  D Muck-Seler; D Pericić
Journal:  J Neural Transm Gen Sect       Date:  1993

6.  The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. III: The mechanistic basis for supersensitivity to the LSD stimulus following serotonin depletion.

Authors:  D Fiorella; S Helsley; D S Lorrain; R A Rabin; J C Winter
Journal:  Psychopharmacology (Berl)       Date:  1995-10       Impact factor: 4.530

7.  Search for correlations between serotonin 5-HT1A receptor expression and cognitive functions--a strategy in translational psychopharmacology.

Authors:  Jacqueline Borg; Bengt Andrée; Johan Lundberg; Christer Halldin; Lars Farde
Journal:  Psychopharmacology (Berl)       Date:  2006-03-16       Impact factor: 4.530

8.  Effect of pindolol on the L-5-HTP-induced increase in plasma prolactin and cortisol concentrations in man.

Authors:  H Y Meltzer; M Maes
Journal:  Psychopharmacology (Berl)       Date:  1994-05       Impact factor: 4.530

Review 9.  Differential changes in serotonin 5-HT1A and 5-HT2 receptor binding in patients with chronic schizophrenia.

Authors:  T Hashimoto; N Kitamura; Y Kajimoto; Y Shirai; O Shirakawa; T Mita; N Nishino; C Tanaka
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

10.  Effect of 8-hydroxy-2-(N,N-di-n-propylamino)tetralin and MDMA on the discriminative stimulus effects of the classical hallucinogen DOM in rats.

Authors:  Nantaka Khorana; Richard Young; Richard A Glennon
Journal:  Pharmacol Biochem Behav       Date:  2008-08-17       Impact factor: 3.533

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