Literature DB >> 20462485

Vesicle transport: a new player in APP trafficking.

David J Owen1, Brett M Collins.   

Abstract

The trafficking of the amyloid precursor protein (APP) is critical for controlling the generation of the toxic A beta peptide that is central to amyloid formation in Alzheimer's disease. A new study reveals a key role for the AP4 adaptor protein complex in the Golgi-to-endosome trafficking of APP. (c) 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20462485     DOI： 10.1016/j.cub.2010.03.017

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  4 in total

1.  Rotenone-dependent changes of anterograde motor protein expression and mitochondrial mobility in brain areas related to neurodegenerative diseases.

Authors:  Thaiany Q Melo; Aline M D'unhao; Stephanie A Martins; Karen L G Farizatto; Rodrigo S Chaves; Merari F R Ferrari
Journal:  Cell Mol Neurobiol       Date:  2012-12-22       Impact factor: 5.046

2.  Expression and processing of fluorescent fusion proteins of amyloid precursor protein (APP).

Authors:  Kathleen Coughlan; Xiangping Huang; Xiangyuan He; Charlotte H Y Chung; Guangpu Li; Jordan Tang
Journal:  Biochim Biophys Acta       Date:  2013-03-19

3.  FUSE: a profit maximization approach for functional summarization of biological networks.

Authors:  Boon-Siew Seah; Sourav S Bhowmick; C Forbes Dewey; Hanry Yu
Journal:  BMC Bioinformatics       Date:  2012-03-21       Impact factor: 3.169

4.  The Amyloid Precursor Protein of Alzheimer's Disease Clusters at the Organelle/Microtubule Interface on Organelles that Bind Microtubules in an ATP Dependent Manner.

Authors:  James W Stevenson; Eliza A Conaty; Rylie B Walsh; Paul J Poidomani; Colin M Samoriski; Brianne J Scollins; Joseph A DeGiorgis
Journal:  PLoS One       Date:  2016-01-27       Impact factor: 3.240
  4 in total

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