BACKGROUND: The objective of this study was to evaluate the performance of a new system for closed-loop control of propofol administration using the bispectral index (BIS) under total intravenous anesthesia in the index values of middle-to-deep depth of anaesthesia. METHODS: In this study 20 adult patients anesthetized with propofol and remifentanil were investigated. The propofol infusion was carried out using a fuzzy-PD+I controller with a target BIS value of 40. RESULTS: Closed-loop control was able to provide maintenance of anesthesia and adequate operating conditions for all patients. The following quality control criteria were calculated: median performance error (MDPE; 0.16%, SD +/-1.4%), median absolute performance error (MDAPE; 6.9%, SD +/-2.8%) and wobble (6.8%, SD +/-2.5%). CONCLUSION: The present study showed the clinical feasibility of the controller compared to existing devices regarding a high level of quality criteria of a model with an implemented fuzzy-PD+I structure controlling depth of hypnosis.
BACKGROUND: The objective of this study was to evaluate the performance of a new system for closed-loop control of propofol administration using the bispectral index (BIS) under total intravenous anesthesia in the index values of middle-to-deep depth of anaesthesia. METHODS: In this study 20 adult patients anesthetized with propofol and remifentanil were investigated. The propofol infusion was carried out using a fuzzy-PD+I controller with a target BIS value of 40. RESULTS: Closed-loop control was able to provide maintenance of anesthesia and adequate operating conditions for all patients. The following quality control criteria were calculated: median performance error (MDPE; 0.16%, SD +/-1.4%), median absolute performance error (MDAPE; 6.9%, SD +/-2.8%) and wobble (6.8%, SD +/-2.5%). CONCLUSION: The present study showed the clinical feasibility of the controller compared to existing devices regarding a high level of quality criteria of a model with an implemented fuzzy-PD+I structure controlling depth of hypnosis.
Authors: Tom De Smet; Michel M R F Struys; Martine M Neckebroek; Kristof Van den Hauwe; Sjoert Bonte; Eric P Mortier Journal: Anesth Analg Date: 2008-10 Impact factor: 5.108
Authors: A Gentilini; M Rossoni-Gerosa; C W Frei; R Wymann; M Morari; A M Zbinden; T W Schnider Journal: IEEE Trans Biomed Eng Date: 2001-08 Impact factor: 4.538
Authors: Ashraf A Dahaba; Markus Mattweber; Andreas Fuchs; Wilhelm Zenz; Peter H Rehak; Werner F List; Helfried Metzler Journal: Anesth Analg Date: 2004-09 Impact factor: 5.108
Authors: Michel M R F Struys; Tom De Smet; Scott Greenwald; Anthony R Absalom; Servaas Bingé; Eric P Mortier Journal: Anesthesiology Date: 2004-03 Impact factor: 7.892