Literature DB >> 20459208

Analysis of flow patterns in a patient-specific aortic dissection model.

Z Cheng1, F P P Tan, C V Riga, C D Bicknell, M S Hamady, R G J Gibbs, N B Wood, X Y Xu.   

Abstract

Aortic dissection is the most common acute catastrophic event affecting the thoracic aorta. The majority of patients presenting with an uncomplicated type B dissection are treated medically, but 25% of these patients develop subsequent aneurysmal dilatation of the thoracic aorta. This study aimed at gaining more detailed knowledge of the flow phenomena associated with this condition. Morphological features and flow patterns in a dissected aortic segment of a presurgery type B dissection patient were analyzed based on computed tomography images acquired from the patient. Computational simulations of blood flow in the patient-specific model were performed by employing a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport turbulence model implemented in ANSYS CFX 11. Our results show that the dissected aorta is dominated by locally highly disturbed, and possibly turbulent, flow with strong recirculation. A significant proportion (about 80%) of the aortic flow enters the false lumen, which may further increase the dilatation of the aorta. High values of wall shear stress have been found around the tear on the true lumen wall, perhaps increasing the likelihood of expanding the tear. Turbulence intensity in the tear region reaches a maximum of 70% at midsystolic deceleration phase. Incorporating the non-Newtonian behavior of blood into the same transitional flow model has yielded a slightly lower peak wall shear stress and higher maximum turbulence intensity without causing discernible changes to the distribution patterns. Comparisons between the laminar and turbulent flow simulations show a qualitatively similar distribution of wall shear stress but a significantly higher magnitude with the transitional turbulence model.

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Year:  2010        PMID: 20459208     DOI: 10.1115/1.4000964

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  22 in total

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Journal:  J Cardiothorac Surg       Date:  2014-12-09       Impact factor: 1.637

2.  Predicting aortic enlargement in type B aortic dissection.

Authors:  Santi Trimarchi; Frederik H W Jonker; Guido H W van Bogerijen; Jip L Tolenaar; Frans L Moll; Martin Czerny; Himanshu J Patel
Journal:  Ann Cardiothorac Surg       Date:  2014-05

3.  Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models.

Authors:  Mona Alimohammadi; Joseph M Sherwood; Morad Karimpour; Obiekezie Agu; Stavroula Balabani; Vanessa Díaz-Zuccarini
Journal:  Biomed Eng Online       Date:  2015-04-15       Impact factor: 2.819

4.  A patient-specific study of type-B aortic dissection: evaluation of true-false lumen blood exchange.

Authors:  Duanduan Chen; Matthias Müller-Eschner; Hendrik von Tengg-Kobligk; David Barber; Dittmar Böckler; Rod Hose; Yiannis Ventikos
Journal:  Biomed Eng Online       Date:  2013-07-06       Impact factor: 2.819

Review 5.  A perspective review on numerical simulations of hemodynamics in aortic dissection.

Authors:  Wan Naimah Wan Ab Naim; Poo Balan Ganesan; Zhonghua Sun; Kok Han Chee; Shahrul Amry Hashim; Einly Lim
Journal:  ScientificWorldJournal       Date:  2014-02-03

6.  Assessment of wall elasticity variations on intraluminal haemodynamics in descending aortic dissections using a lumped-parameter model.

Authors:  Paula A Rudenick; Bart H Bijnens; Patrick Segers; David García-Dorado; Arturo Evangelista
Journal:  PLoS One       Date:  2015-04-16       Impact factor: 3.240

7.  Experience With Fenestrated Endovascular Repair of Juxtarenal Abdominal Aortic Aneurysms at a Single Center.

Authors:  Zhongzhou Hu; Yue Li; Ran Peng; Jie Liu; Tao Zhang; Wei Guo
Journal:  Medicine (Baltimore)       Date:  2016-03       Impact factor: 1.889

8.  The characteristics of distal tears affect false lumen thrombosis rate after thoracic endovascular aortic repair for acute type B dissection.

Authors:  Da Li; Ding Yuan; Liqing Peng; Tinghui Zheng; Yubo Fan
Journal:  Interact Cardiovasc Thorac Surg       Date:  2021-10-29

9.  Stroke propensity is increased under atrial fibrillation hemodynamics: a simulation study.

Authors:  Hyo Won Choi; Jose A Navia; Ghassan S Kassab
Journal:  PLoS One       Date:  2013-09-05       Impact factor: 3.240

10.  Multi-modality image-based computational analysis of haemodynamics in aortic dissection.

Authors:  Desmond Dillon-Murphy; Alia Noorani; David Nordsletten; C Alberto Figueroa
Journal:  Biomech Model Mechanobiol       Date:  2015-09-28
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