Literature DB >> 20458850

Rapidly evolving liver decompensation with some remarkable features 14 years after biliopancreatic derivation: a case report and literature review.

J L van Dongen1, P P Michielsen, G G Van den Eynden, P A Pelckmans, S M Francque.   

Abstract

Because of the rising incidence of obesity the use of bariatric surgery is also increasing. For the obese it is the only treatment with a proven long-term benefit on weight, comorbidities including non alcoholic steatohepatitis, and long-term mortality. There are, however, several reports on hepatic complications after bariatric surgery leading to malabsorption. The risk of liver decompensation or cirrhosis is one of the reasons jejunoileal bypass has been abandoned. Hepatic complications following Roux-en-Y gastric bypass and biliopancreatic derivation (BPD) are also reported but never beyond 2 years of follow-up. There is only one confirmed case of development of cirrhosis following BPD which presented 10 months after surgery. We present a case of a 39-year-old patient who developed rapidly evolving, and ultimately fatal, liver decompensation in previously unknown cirrhosis, 14 years after BPD. This is the first report of a severe hepatic complication such a long time after a BPD. Existing literature on hepatic complications after bariatric surgery is discussed as are 2 coincidental findings of pronounced ductular reaction on histology and autoimmune haemolytic anaemia.

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Year:  2010        PMID: 20458850

Source DB:  PubMed          Journal:  Acta Gastroenterol Belg        ISSN: 1784-3227            Impact factor:   1.316


  3 in total

1.  What Is a Favourable Risk-Benefit Profile Concerning Metabolic Surgery for Patients with Type 2 Diabetes?

Authors:  Michel Gagner
Journal:  Obes Surg       Date:  2017-04       Impact factor: 4.129

Review 2.  Monitoring of Liver Function Tests after Roux-en-Y Gastric Bypass: An Examination of Evidence Base.

Authors:  Kamal K Mahawar; Chetan Parmar; Yitka Graham; Nimantha De Alwis; William R J Carr; Neil Jennings; Peter K Small
Journal:  Obes Surg       Date:  2016-10       Impact factor: 4.129

3.  Cirrhosis following single anastomosis duodeno-ileal switch: A case report.

Authors:  Vincent Kirkpatrick; Rena C Moon; Andre F Teixeira; Muhammad A Jawad
Journal:  Int J Surg Case Rep       Date:  2018-03-17
  3 in total

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