C Iavazzo1, N Vitoratos. 1. Second Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece. christosiavazzo@hotmail.com
Abstract
INTRODUCTION: Polycystic ovarian syndrome (PCOS) is a common disease of the endocrine system among the women of reproductive age with an incidence ranging from 5 to 10%. METHOD: This study is a mini-review of pregnancy and perinatal outcome in women with PCOS. RESULTS: The syndrome is associated with increased risk of pregnancy complications such as gestational diabetes, gestational hypertension, preeclampsia, and preterm labor, while no strong association was found with congenital anomalies or spontaneous miscarriages. Furthermore, women with PCOS seem to experience increased risk of cesarean delivery while their newborns face increased perinatal morbidity and mortality. Metformin use seems to reduce the risk of obstetrical complications; however, prospective studies are necessary on the field. CONCLUSION: Further studies should be organised in order to evaluate the role of PCOS in pregnancy.
INTRODUCTION:Polycystic ovarian syndrome (PCOS) is a common disease of the endocrine system among the women of reproductive age with an incidence ranging from 5 to 10%. METHOD: This study is a mini-review of pregnancy and perinatal outcome in women with PCOS. RESULTS: The syndrome is associated with increased risk of pregnancy complications such as gestational diabetes, gestational hypertension, preeclampsia, and preterm labor, while no strong association was found with congenital anomalies or spontaneous miscarriages. Furthermore, women with PCOS seem to experience increased risk of cesarean delivery while their newborns face increased perinatal morbidity and mortality. Metformin use seems to reduce the risk of obstetrical complications; however, prospective studies are necessary on the field. CONCLUSION: Further studies should be organised in order to evaluate the role of PCOS in pregnancy.
Authors: Ellane R Cleys; Jennifer L Halleran; Vanessa A Enriquez; Juliano C da Silveira; Rachel C West; Quinton A Winger; Russell V Anthony; Jason E Bruemmer; Colin M Clay; Gerrit J Bouma Journal: PLoS One Date: 2015-02-12 Impact factor: 3.240