| Literature DB >> 2045704 |
T Anai1, Y Hirota, M Oga, J Yoshimatsu, I Miyakawa.
Abstract
Using PIVKA-II and Hepaplastin test, 5 neonates exposed to anticonvulsant drugs in utero were assessed 5 days after birth. None showed any sign of clinical bleeding, but all had PIVKA-II values over 1 microgram/ml. In controls, only 96 of 1,166 (8.2%) neonates had PIVKA-II values over 1 microgram/ml. The difference in the incidence rate was significant (p less than 0.005). Three of 5 epileptic mothers received valproatic acid and/or diazepam but no barbiturates and/or hydantoin.Entities:
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Year: 1991 PMID： 2045704
Source DB: PubMed Journal: Nihon Sanka Fujinka Gakkai Zasshi ISSN： 0300-9165