| Literature DB >> 2045684 |
H Wefers1, B C Melnik, M Flür, C Bluhm, P Lehmann, G Plewig.
Abstract
Irradiation with suberythemal doses of either UV-A or UV-B yielded an increase in the amount of stratum corneum lipids extracted from the lumbar skin area of 20 volunteers. These lipids were quantified after separation by high-performance thin-layer chromatography. Ten subfractions in the ceramide region were separated; two of them (fractions 7a and 7b) were only detectable after UV-A or UV-B irradiation. Improvement of barrier function after UV irradiation of human skin with suberythemal doses may be related to an increase in the stratum corneum ceramides.Entities:
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Year: 1991 PMID: 2045684 DOI: 10.1111/1523-1747.ep12476124
Source DB: PubMed Journal: J Invest Dermatol ISSN: 0022-202X Impact factor: 8.551