Literature DB >> 20456699

Human immunodeficiency virus test-seeking blood donors in a large blood bank in São Paulo, Brazil.

Thelma Goncalez1, Ester Sabino, Nanci Sales, Yea-Hung Chen, Dalton Chamone, Michael Busch, Edward Murphy, Brian Custer, Willi McFarland.   

Abstract

BACKGROUND: Persons with human immunodeficiency virus (HIV) risk behaviors are excluded from donation to reduce the risk of transfusion-transmitted infection. Persons donating to be tested for HIV may therefore deny risk behaviors. STUDY DESIGN AND METHODS: A random sample of donors completed a survey on motivations, knowledge, and attitudes on the screening process. Donors were considered test seekers if they agreed with two statements "I think that blood donation is a good, fast, and anonymous way to get my blood tested" and "I donate to get my test results." This study was conducted from June to November 2006 at the largest blood bank in São Paulo, Brazil.
RESULTS: Of 3061 participants, 208 (7%) were test seekers. They tended to be male and had a lower educational level. They were more likely to have incorrect knowledge about blood safety (e.g., not knowing that a unit can test antibody negative and still transmit infection, 50% vs. 42%, p = 0.02), express dissatisfaction with screening questions (e.g., feeling that important questions were not asked, 14% vs. 5%, p < 0.01), and concur that donors do not answer questions truthfully (e.g., donors have more sexual partners than they admit, 29% vs. 18%, p < 0.01). Test seekers were more likely to believe that it is acceptable to donate blood to get tested for HIV (41% vs. 10%, p < 0.01).
CONCLUSIONS: Test-seeking motivation, coupled with low knowledge of window period risk, is counter to improving blood safety and to donor prevention needs. Donor education needs to be improved along with availability of appropriate HIV counseling and testing.
© 2010 American Association of Blood Banks.

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Year:  2010        PMID: 20456699      PMCID: PMC2981410          DOI: 10.1111/j.1537-2995.2010.02650.x

Source DB:  PubMed          Journal:  Transfusion        ISSN: 0041-1132            Impact factor:   3.157


  29 in total

1.  Strong preference "to donate" among HIV-positive blood donors in Zimbabwe.

Authors:  D Mvere; R Shamu; R Makoni; S Lloyd; E Nhau; W McFarland
Journal:  Lancet       Date:  1996-03-30       Impact factor: 79.321

2.  Prevalence, incidence, and residual risk of human immunodeficiency virus among community and replacement first-time blood donors in São Paulo, Brazil.

Authors:  Claudia C Barreto; Ester C Sabino; Thelma T Gonçalez; Megan E Laycock; Brandee L Pappalardo; Nanci A Salles; David J Wright; Dalton F Chamone; Michael P Busch
Journal:  Transfusion       Date:  2005-11       Impact factor: 3.157

3.  Audiovisual touch-screen computer-assisted self-interviewing for donor health histories: results from two years experience with the system.

Authors:  Louis M Katz; Paul D Cumming; Edward L Wallace; Philip S Abrams
Journal:  Transfusion       Date:  2005-02       Impact factor: 3.157

4.  A new strategy for estimating risks of transfusion-transmitted viral infections based on rates of detection of recently infected donors.

Authors:  Michael P Busch; Simone A Glynn; Susan L Stramer; D Michael Strong; Sally Caglioti; David J Wright; Brandee Pappalardo; Steven H Kleinman
Journal:  Transfusion       Date:  2005-02       Impact factor: 3.157

5.  Human immunodeficiency virus type 1-infected blood donors: behavioral characteristics and reasons for donation. The HIV Blood Donor Study Group.

Authors:  L S Doll; L R Petersen; C R White; J W Ward
Journal:  Transfusion       Date:  1991-10       Impact factor: 3.157

6.  Detection of HIV-1 and HCV infections among antibody-negative blood donors by nucleic acid-amplification testing.

Authors:  Susan L Stramer; Simone A Glynn; Steven H Kleinman; D Michael Strong; Sally Caglioti; David J Wright; Roger Y Dodd; Michael P Busch
Journal:  N Engl J Med       Date:  2004-08-19       Impact factor: 91.245

7.  Demographic characteristics and prevalence of serologic markers among donors who use the confidential unit exclusion process: the Retrovirus Epidemiology Donor Study.

Authors:  J J Korelitz; A E Williams; M P Busch; T F Zuck; H E Ownby; L J Matijas; D J Wright
Journal:  Transfusion       Date:  1994-10       Impact factor: 3.157

8.  Estimates of infectious disease risk factors in US blood donors. Retrovirus Epidemiology Donor Study.

Authors:  A E Williams; R A Thomson; G B Schreiber; K Watanabe; J Bethel; A Lo; S H Kleinman; C G Hollingsworth; G J Nemo
Journal:  JAMA       Date:  1997-03-26       Impact factor: 56.272

9.  The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study.

Authors:  G B Schreiber; M P Busch; S H Kleinman; J J Korelitz
Journal:  N Engl J Med       Date:  1996-06-27       Impact factor: 91.245

Review 10.  Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies.

Authors:  Esther E Freeman; Helen A Weiss; Judith R Glynn; Pamela L Cross; James A Whitworth; Richard J Hayes
Journal:  AIDS       Date:  2006-01-02       Impact factor: 4.177

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  14 in total

1.  Human immunodeficiency virus prevalence, incidence, and residual risk of transmission by transfusions at Retrovirus Epidemiology Donor Study-II blood centers in Brazil.

Authors:  Ester C Sabino; Thelma T Gonçalez; Anna Bárbara Carneiro-Proietti; Moussa Sarr; João Eduardo Ferreira; Divaldo A Sampaio; Nanci A Salles; David J Wright; Brian Custer; Michael Busch
Journal:  Transfusion       Date:  2011-10-07       Impact factor: 3.157

2.  One window-period donation in two years of individual donor-nucleic acid test screening for hepatitis B, hepatitis C and human immunodeficiency virus.

Authors:  José Eduardo Levi; Ricardo Antonio D'Almeida Pereira; Márcia Bernardino de Carvalho Polite; Mariza Aparecida Mota; Silvia Patricia Nunez; João Renato Rebello Pinho; José Mauro Kutner
Journal:  Rev Bras Hematol Hemoter       Date:  2013

3.  Knowledge of HIV testing and attitudes towards blood donation at three blood centres in Brazil.

Authors:  C Miranda; E Moreno; R Bruhn; N M Larsen; D J Wright; C D L Oliveira; A B F Carneiro-Proietti; P Loureiro; C de Almeida-Neto; B Custer; E C Sabino; T T Gonçalez
Journal:  Vox Sang       Date:  2013-12-09       Impact factor: 2.144

4.  What weighs more-low compliance with self-deferral or minor medical procedures? Explaining the high rate of hepatitis C virus window-period donations in Poland.

Authors:  Michal Czerwinski; Piotr Grabarczyk; Malgorzata Stepien; Dorota Kubicka-Russel; Katarzyna Tkaczuk; Ewa Brojer; Magdalena Rosinska
Journal:  Transfusion       Date:  2017-05-28       Impact factor: 3.157

5.  The National Heart, Lung, and Blood Institute retrovirus epidemiology donor studies (Retrovirus Epidemiology Donor Study and Retrovirus Epidemiology Donor Study-II): twenty years of research to advance blood product safety and availability.

Authors:  Steven Kleinman; Melissa R King; Michael P Busch; Edward L Murphy; Simone A Glynn
Journal:  Transfus Med Rev       Date:  2012-05-24

6.  Blood Donor Test-Seeking Motivation and Prior HIV Testing Experiences in São Paulo, Brazil.

Authors:  Hong-Ha M Truong; Paula F Blatyta; Fernanda M Santos; Sandra Montebello; Sandra P D Esposti; Fatima N Hangai; Nanci Alves Salles; Alfredo Mendrone; Ester C Sabino; Willi McFarland; Thelma T Gonçalez
Journal:  AIDS Behav       Date:  2015-09

7.  Factors associated with failure of clinical screening among blood donors who have altered serological results in the Centro Regional de Hemoterapia de Ribeirão Preto.

Authors:  Oranice Ferreira; Afonso Dinis Costa Passos
Journal:  Rev Bras Hematol Hemoter       Date:  2012

8.  Undisclosed human immunodeficiency virus risk factors identified through a computer-based questionnaire program among blood donors in Brazil.

Authors:  Paula Fraiman Blatyta; Brian Custer; Thelma Terezinha Gonçalez; Rebecca Birch; Maria Esther Lopes; Maria Ines Lopes Ferreira; Anna Barbara Carneiro Proietti; Ester Cerdeira Sabino; Kimberly Page; Cesar de Almeida-Neto
Journal:  Transfusion       Date:  2013-03-22       Impact factor: 3.157

9.  The National Heart, Lung, and Blood Institute Recipient Epidemiology and Donor Evaluation Study (REDS-III): a research program striving to improve blood donor and transfusion recipient outcomes.

Authors:  Steven Kleinman; Michael P Busch; Edward L Murphy; Hua Shan; Paul Ness; Simone A Glynn
Journal:  Transfusion       Date:  2013-11-04       Impact factor: 3.157

10.  Knowledge of AIDS and HIV transmission among drug users in Rio de Janeiro, Brazil.

Authors:  Neilane Bertoni; Merril Singer; Cosme Mfp Silva; Scott Clair; Monica Malta; Francisco I Bastos
Journal:  Harm Reduct J       Date:  2011-02-15
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