Literature DB >> 20455048

[Long-term remission of malignant melanoma stage IV after antigen-specific immunotherapy].

Antje Neumann1, Julia Karbach, Akin Atmaca, Elke Jäger.   

Abstract

This case report describes the clinical course of a patient with progressing metastatic melanoma (M1a) under standard chemotherapy, followed by long-term partial remission of disease under treatment with experimental, specific immunotherapy. Detectable specific immune responses demonstrate the correlation between continued tumor regression and the administered specific immunotherapy.

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Year:  2010        PMID： 20455048     DOI： 10.1007/s00063-010-1041-7

Source DB:  PubMed          Journal:  Med Klin (Munich)        ISSN： 0723-5003


  5 in total

1.  Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo.

Authors:  E Jäger; M Ringhoffer; H P Dienes; M Arand; J Karbach; D Jäger; C Ilsemann; M Hagedorn; F Oesch; A Knuth
Journal:  Int J Cancer       Date:  1996-07-03       Impact factor: 7.396

2.  Clonal expansion of Melan A-specific cytotoxic T lymphocytes in a melanoma patient responding to continued immunization with melanoma-associated peptides.

Authors:  E Jäger; M Maeurer; H Höhn; J Karbach; D Jäger; Z Zidianakis; A Bakhshandeh-Bath; J Orth; C Neukirch; A Necker; T E Reichert; A Knuth
Journal:  Int J Cancer       Date:  2000-05-15       Impact factor: 7.396

3.  Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients.

Authors:  Elke Jäger; Julia Karbach; Sacha Gnjatic; Antje Neumann; Armin Bender; Danila Valmori; Maha Ayyoub; Erika Ritter; Gerd Ritter; Dirk Jäger; Dennis Panicali; Eric Hoffman; Linda Pan; Herbert Oettgen; Lloyd J Old; Alexander Knuth
Journal:  Proc Natl Acad Sci U S A       Date:  2006-09-19       Impact factor: 11.205

Review 4.  Cancer/testis (CT) antigens: potential targets for immunotherapy.

Authors:  Otavia L Caballero; Yao-Tseng Chen
Journal:  Cancer Sci       Date:  2009-08-01       Impact factor: 6.716

Review 5.  Human tumor antigens recognized by T lymphocytes.

Authors:  T Boon; P van der Bruggen
Journal:  J Exp Med       Date:  1996-03-01       Impact factor: 14.307
  5 in total

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