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Literature DB >> 20454738

Comparative quantitation of proteome alterations induced by aging or immortalization in primary human fibroblasts and keratinocytes for clinical applications.

Adrian Sprenger¹, Victoria Küttner, Martin L Biniossek, Christine Gretzmeier, Melanie Boerries, Claudia Mack, Cristina Has, Leena Bruckner-Tuderman, Jörn Dengjel.

Abstract

We monitor proteome changes of primary human skin fibroblasts and keratinocytes during cell culture and compare them to respective immortalized cell lines using stable isotope labeling by amino acids to address their suitability as cell models for clinical disease proteomics.

Entities: Species

Mesh：

Substances：
Proteome

Year: 2010 PMID： 20454738 DOI： 10.1039/c003962d

Source DB: PubMed Journal: Mol Biosyst ISSN： 1742-2051

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Cited

11 in total

1. [New developments in hereditary blistering skin diseases].

Authors: L Bruckner-Tuderman
Journal: Hautarzt Date: 2013-01 Impact factor: 0.751

2. Kindlin-1 and -2 have overlapping functions in epithelial cells implications for phenotype modification.

Authors: Yinghong He; Philipp Esser; Anja Heinemann; Leena Bruckner-Tuderman; Cristina Has
Journal: Am J Pathol Date: 2011-03 Impact factor: 4.307

Review 3. Human dermal fibroblasts in psychiatry research.

Authors: S Kálmán; K A Garbett; Z Janka; K Mirnics
Journal: Neuroscience Date: 2016-02-09 Impact factor: 3.590

Review 4. Tissue-engineered kidney disease models.

Authors: Teresa M Desrochers; Erica Palma; David L Kaplan
Journal: Adv Drug Deliv Rev Date: 2013-12-17 Impact factor: 15.470

5. Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization.

Authors: Adrian Sprenger; Sebastian Weber; Mostafa Zarai; Rudolf Engelke; Juliana M Nascimento; Christine Gretzmeier; Martin Hilpert; Melanie Boerries; Cristina Has; Hauke Busch; Leena Bruckner-Tuderman; Jörn Dengjel
Journal: Mol Cell Proteomics Date: 2013-05-30 Impact factor: 5.911

Review 6. Primary skin fibroblasts as a model of Parkinson's disease.

Authors: Georg Auburger; Michael Klinkenberg; Jessica Drost; Katrin Marcus; Blas Morales-Gordo; Wolfram S Kunz; Ulrich Brandt; Vania Broccoli; Heinz Reichmann; Suzana Gispert; Marina Jendrach
Journal: Mol Neurobiol Date: 2012-02-19 Impact factor: 5.590

Comparative quantitation of proteome alterations induced by aging or immortalization in primary human fibroblasts and keratinocytes for clinical applications.

1. [New developments in hereditary blistering skin diseases].

2. Kindlin-1 and -2 have overlapping functions in epithelial cells implications for phenotype modification.

Review 3. Human dermal fibroblasts in psychiatry research.

Review 4. Tissue-engineered kidney disease models.

5. Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization.

Review 6. Primary skin fibroblasts as a model of Parkinson's disease.

7. Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand.

8. Global remodelling of cellular microenvironment due to loss of collagen VII.

9. Altered MCM protein levels and autophagic flux in aged and systemic sclerosis dermal fibroblasts.

10. The Effect of Herbal Medicinal Products on Psoriasis-Like Keratinocytes.