Literature DB >> 20453668

Association of environmental tobacco smoke exposure with elevated home blood pressure in Japanese women: the Ohasama study.

Mami Seki1, Ryusuke Inoue, Takayoshi Ohkubo, Masahiro Kikuya, Azusa Hara, Hirohito Metoki, Takuo Hirose, Megumi Tsubota-Utsugi, Kei Asayama, Atsuhiro Kanno, Taku Obara, Haruhisa Hoshi, Kazuhito Totsune, Hiroshi Satoh, Yutaka Imai.   

Abstract

OBJECTIVE: Only a few of numerous epidemiological studies have demonstrated a positive association between environmental tobacco smoke (ETS) exposure and blood pressure (BP), despite experimental studies showing such a positive association. The association between home blood pressure (HBP) and ETS exposure was investigated in the general population.
METHODS: Five hundred and seventy-nine nonsmoking Japanese women were enrolled. The participants were classified into four categories according to their responses to a self-administered questionnaire: unexposed women (non-ETS), women exposed at home [ETS(home)], at the workplace/other places [ETS(work/other)] and at home and at the workplace/other places [ETS(both)]. Variables were compared using analysis of covariance adjusted for age, marital status, body mass index, diabetes mellitus, stroke, heart disease, hyperlipidemia, alcohol intake, salt intake and activity levels.
RESULTS: In participants without antihypertensive medication, systolic morning HBP in ETS(both) was 4 mmHg higher than that in non-ETS (116.8 +/- 1.01 vs. 113.1 +/- 1.08 mmHg, P = 0.02) and systolic morning HBP in ETS(home) and systolic evening HBP in ETS(both) were 3 mmHg higher than those in non-ETS (116.2 +/- 1.07 vs. 113.1 +/- 1.08 mmHg, P = 0.04; and 115.3 +/- 1.02 vs. 111.9 +/- 1.09 mmHg, P = 0.03, respectively). In participants with antihypertensive medication, ETS exposure status was not significantly associated with increased HBP levels.
CONCLUSIONS: A positive association between HBP levels and ETS exposure was confirmed. HBP measurement is recommended in population-based studies investigating the effects of ETS exposure. ETS exposure may increase BP, thereby synergistically contributing to unfavorable cardiovascular outcomes along with other deleterious effects of ETS.

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Year:  2010        PMID: 20453668     DOI: 10.1097/HJH.0b013e32833a3911

Source DB:  PubMed          Journal:  J Hypertens        ISSN: 0263-6352            Impact factor:   4.844


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