Literature DB >> 20453119

Assessing the potential of an induced-mutation strategy for avermectin overproducers.

Hong Gao1, Mei Liu, Ying Zhuo, Xianlong Zhou, Jintao Liu, Difei Chen, Wenquan Zhang, Zhongxuan Gou, Peng Shang, Lixin Zhang.   

Abstract

Mutant libraries of avermectin-producing Streptomyces avermitilis strains were constructed by different mutagenesis strategies. A metric was applied to assess the mutation spectrum by calculating the distribution of average phenotypic distance of each population. The results showed for the first time that a microgravity environment could introduce larger phenotype distribution and diversity than UV and N-methyl-N-nitro-N-nitrosoguanidine (NTG) could.

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Year:  2010        PMID： 20453119      PMCID： PMC2897423          DOI： 10.1128/AEM.01682-09

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  19 in total

1.  [Increasing biosynthesis of avermectins of Streptomyces avermitilis UCM Ac 2161 under the effect N-methyl-N'-nitro-N-nitrosoguanidine].

Authors:  T V Petruk; L O Biliavs'ka; V Ie Kozyryts'ka; M S Mukvych
Journal:  Mikrobiol Z       Date:  2004 Nov-Dec

2.  Microbial antibiotic production aboard the International Space Station.

Authors:  M R Benoit; W Li; L S Stodieck; K S Lam; C L Winther; T M Roane; D M Klaus
Journal:  Appl Microbiol Biotechnol       Date:  2005-08-10       Impact factor: 4.813

3.  A containerless levitation setup for liquid processing in a superconducting magnet.

Authors:  Hui-Meng Lu; Da-Chuan Yin; Hai-Sheng Li; Li-Qiang Geng; Chen-Yan Zhang; Qin-Qin Lu; Yun-Zhu Guo; Wei-Hong Guo; Peng Shang; Nobuko I Wakayama
Journal:  Rev Sci Instrum       Date:  2008-09       Impact factor: 1.523

4.  Life sciences: microorganisms in the space environment.

Authors:  G Horneck; H Bücker; G Reitz; H Requardt; K Dose; K D Martens; H D Mennigmann; P Weber
Journal:  Science       Date:  1984-07-13       Impact factor: 47.728

5.  Mutagenic DNA repair in Streptomyces.

Authors:  J Stonesifer; R H Baltz
Journal:  Proc Natl Acad Sci U S A       Date:  1985-02       Impact factor: 11.205

6.  The effects of microgravity on induced mutation in Escherichia coli and Saccharomyces cerevisiae.

Authors:  A Takahashi; K Ohnishi; S Takahashi; M Masukawa; K Sekikawa; T Amano; T Nakano; S Nagaoka; T Ohnishi
Journal:  Adv Space Res       Date:  2001       Impact factor: 2.152

7.  The effect of inorganic phosphate on the production of avermectin in Streptomyces avermitilis.

Authors:  E Curdová; V Jechová; J Zima; Z Vanĕk
Journal:  J Basic Microbiol       Date:  1989       Impact factor: 2.281

8.  [Selection of high avermectins producing strain and identification of avermectin B1].

Authors:  Y Song; G M Cao; Z Chen; J L Li
Journal:  Sheng Wu Gong Cheng Xue Bao       Date:  2000-01

9.  Preliminary report on the biological effects of space flight on the producing strain of a new immunosuppressant, Kanglemycin C.

Authors:  Jianqin Zhou; Chenghang Sun; Nanjin Wang; Rongmei Gao; Shuoke Bai; Huanrong Zheng; Xuefu You; Rongfeng Li
Journal:  J Ind Microbiol Biotechnol       Date:  2006-04-12       Impact factor: 3.346

10.  Medium optimization for the production of avermectin B1a by Streptomyces avermitilis 14-12A using response surface methodology.

Authors:  Hong Gao; Mei Liu; Jintao Liu; Huanqin Dai; Xianlong Zhou; Xiangyang Liu; Ying Zhuo; Wenquan Zhang; Lixin Zhang
Journal:  Bioresour Technol       Date:  2009-04-07       Impact factor: 9.642
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  5 in total

1.  Secondary metabolism in simulated microgravity and space flight.

Authors:  Hong Gao; Zhiheng Liu; Lixin Zhang
Journal:  Protein Cell       Date:  2011-11       Impact factor: 14.870

2.  Implication of mutagenesis and precursor supplementation towards the enhancement of lipstatin (an antiobesity agent) biosynthesis through submerged fermentation using Streptomyces toxytricini.

Authors:  Punit Kumar; Kashyap Kumar Dubey
Journal:  3 Biotech       Date:  2017-12-26       Impact factor: 2.406

3.  Magnetic field is the dominant factor to induce the response of Streptomyces avermitilis in altered gravity simulated by diamagnetic levitation.

Authors:  Mei Liu; Hong Gao; Peng Shang; Xianlong Zhou; Elizabeth Ashforth; Ying Zhuo; Difei Chen; Biao Ren; Zhiheng Liu; Lixin Zhang
Journal:  PLoS One       Date:  2011-10-19       Impact factor: 3.240

4.  A plate method for rapid screening of Ketogulonicigenium vulgare mutants for enhanced 2-keto-l-gulonic acid production.

Authors:  Weichao Yang; Litao Han; Mandlaa Mandlaa; Haihong Zhang; Zhongze Zhang; Hui Xu
Journal:  Braz J Microbiol       Date:  2017-02-21       Impact factor: 2.476

5.  Interrogation of Streptomyces avermitilis for efficient production of avermectins.

Authors:  Jinsong Chen; Mei Liu; Xueting Liu; Jin Miao; Chengzhang Fu; Heyong Gao; Rolf Müller; Qing Zhang; Lixin Zhang
Journal:  Synth Syst Biotechnol       Date:  2016-04-22
  5 in total

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