Literature DB >> 20452964

ZAP-70: an essential kinase in T-cell signaling.

Haopeng Wang1, Theresa A Kadlecek, Byron B Au-Yeung, Hanna E Sjölin Goodfellow, Lih-Yun Hsu, Tanya S Freedman, Arthur Weiss.   

Abstract

ZAP-70 is a cytoplasmic protein tyrosine kinase that plays a critical role in the events involved in initiating T-cell responses by the antigen receptor. Here we review the structure of ZAP-70, its regulation, its role in development and in disease. We also describe a model experimental system in which ZAP-70 function can be interrupted by a small chemical inhibitor.

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Year:  2010        PMID: 20452964      PMCID: PMC2857167          DOI: 10.1101/cshperspect.a002279

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Biol        ISSN: 1943-0264            Impact factor:   10.005


  84 in total

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Journal:  Nat Immunol       Date:  2005-11-06       Impact factor: 25.606

2.  T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster.

Authors:  Rajat Varma; Gabriele Campi; Tadashi Yokosuka; Takashi Saito; Michael L Dustin
Journal:  Immunity       Date:  2006-07       Impact factor: 31.745

3.  ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells.

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Journal:  Blood       Date:  2006-10-12       Impact factor: 22.113

4.  Structural basis for the inhibition of tyrosine kinase activity of ZAP-70.

Authors:  Sebastian Deindl; Theresa A Kadlecek; Tomas Brdicka; Xiaoxian Cao; Arthur Weiss; John Kuriyan
Journal:  Cell       Date:  2007-05-18       Impact factor: 41.582

5.  RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development.

Authors:  Yi Gu; Hee-Don Chae; Jamie E Siefring; Aparna C Jasti; David A Hildeman; David A Williams
Journal:  Nat Immunol       Date:  2006-10-08       Impact factor: 25.606

6.  T cell activation-induced CrkII binding to the Zap70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of Zap70 tyrosine 315.

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Journal:  J Immunol       Date:  2005-12-15       Impact factor: 5.422

Review 7.  Spontaneous development of autoimmune arthritis due to genetic anomaly of T cell signal transduction: Part 1.

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8.  Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.

Authors:  Gabriele Campi; Rajat Varma; Michael L Dustin
Journal:  J Exp Med       Date:  2005-10-10       Impact factor: 14.307

9.  Distinct roles for Syk and ZAP-70 during early thymocyte development.

Authors:  Emil H Palacios; Arthur Weiss
Journal:  J Exp Med       Date:  2007-07-02       Impact factor: 14.307

10.  Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.

Authors:  Tal Ilani; Chand Khanna; Ming Zhou; Timothy D Veenstra; Anthony Bretscher
Journal:  J Cell Biol       Date:  2007-11-19       Impact factor: 10.539

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  154 in total

Review 1.  Immunoreceptor signaling.

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Journal:  J Cell Sci       Date:  2017-02-02       Impact factor: 5.285

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Journal:  Mol Cell       Date:  2016-03-24       Impact factor: 17.970

Review 4.  Impact of gut microbiota on gut-distal autoimmunity: a focus on T cells.

Authors:  Maran L Sprouse; Nicholas A Bates; Krysta M Felix; Hsin-Jung Joyce Wu
Journal:  Immunology       Date:  2019-01-21       Impact factor: 7.397

Review 5.  Signaling in lymphocyte activation.

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Journal:  Cold Spring Harb Perspect Biol       Date:  2015-06-01       Impact factor: 10.005

Review 6.  Selected signalling proteins recruited to the T-cell receptor-CD3 complex.

Authors:  Jatuporn Ngoenkam; Wolfgang W Schamel; Sutatip Pongcharoen
Journal:  Immunology       Date:  2017-09-05       Impact factor: 7.397

Review 7.  Orai1-NFAT signalling pathway triggered by T cell receptor stimulation.

Authors:  Sonal Srikanth; Yousang Gwack
Journal:  Mol Cells       Date:  2013-03-11       Impact factor: 5.034

8.  Retinoic Acid Modulates Hyperactive T Cell Responses and Protects Vitamin A-Deficient Mice against Persistent Lymphocytic Choriomeningitis Virus Infection.

Authors:  Yuejin Liang; Panpan Yi; Xiaofang Wang; Biao Zhang; Zuliang Jie; Lynn Soong; Jiaren Sun
Journal:  J Immunol       Date:  2020-04-13       Impact factor: 5.422

9.  "Cell biology meets physiology: functional organization of vertebrate plasma membranes"--the immunological synapse.

Authors:  Silvia Curado; Sudha Kumari; Michael L Dustin
Journal:  Curr Top Membr       Date:  2013       Impact factor: 3.049

10.  Recruitment of calcineurin to the TCR positively regulates T cell activation.

Authors:  Debjani Dutta; Valarie A Barr; Itoro Akpan; Paul R Mittelstadt; Laishram I Singha; Lawrence E Samelson; Jonathan D Ashwell
Journal:  Nat Immunol       Date:  2016-12-12       Impact factor: 25.606

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