Literature DB >> 20452413

Khat use and monitoring drug use in Europe: the current situation and issues for the future.

Paul Griffiths1, Dominique Lopez, Roumen Sedefov, Ana Gallegos, Brendan Hughes, André Noor, Luis Royuela.   

Abstract

AIM OF THE STUDY: To review the information available on the use of khat (Catha edulis) in the EU, and to assess the future use of this drug and related substances.
MATERIAL AND METHODS: Khat is not controlled by international law and it has not been systematically included in the list of illicit drugs monitored in the EU. The current principal source of information on khat use in Europe is the early-warning system set up to monitor new and emerging drugs. Further information was obtained from official national reports to the EMCDDA and from the scientific literature.
RESULTS: Across Europe, the use of khat is low. Khat use is limited to countries with immigrant communities from countries where khat use is common (such as Ethiopia, Somalia and Kenya). Information on the prevalence of khat use in the general population is scarce. Data on seizures provide an insight on the situation, though these may be difficult to interpret. The most recent estimates suggest that Europe accounts for about 40% of the khat seized worldwide.
CONCLUSION: The shortage of data on the use and patterns of use of khat in Europe does not allow an evaluation of the needs for health and social interventions in communities in which the drug is used. But seizures of the plant are increasing in the EU, and more synthetic derivatives of the pharmacologically active ingredients of the plant (cathine and cathinone) are appearing on the market. Some of these, like mephedrone, have significant potential for future diffusion, and are likely to play a greater role on the European drug scene of the future.
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

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Year:  2010        PMID: 20452413     DOI: 10.1016/j.jep.2010.04.046

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  21 in total

1.  Effects of synthetic cathinones contained in "bath salts" on motor behavior and a functional observational battery in mice.

Authors:  Julie A Marusich; Kateland R Grant; Bruce E Blough; Jenny L Wiley
Journal:  Neurotoxicology       Date:  2012-08-23       Impact factor: 4.294

2.  Effects of chronic khat use on cardiovascular, adrenocortical, and psychological responses to stress in men and women.

Authors:  Mustafa al'Absi; Najat Sayem Khalil; Molham Al Habori; Richard Hoffman; Koji Fujiwara; Lorentz Wittmers
Journal:  Am J Addict       Date:  2013-02-01

Review 3.  Addictions Neuroclinical Assessment: A reverse translational approach.

Authors:  Laura E Kwako; Reza Momenan; Erica N Grodin; Raye Z Litten; George F Koob; David Goldman
Journal:  Neuropharmacology       Date:  2017-03-07       Impact factor: 5.250

4.  Concurrent tobacco and khat use is associated with blunted cardiovascular stress response and enhanced negative mood: a cross-sectional investigation.

Authors:  Mustafa al'Absi; Motohiro Nakajima; Anisa Dokam; Abed Sameai; Mohamed Alsoofi; Najat Saem Khalil; Molham Al Habori
Journal:  Hum Psychopharmacol       Date:  2014-04-07       Impact factor: 1.672

5.  In vitro metabolic profile of mexedrone, a mephedrone analog, studied by high- and low-resolution mass spectrometry.

Authors:  Cristian Camuto; Angelica Guglielmelli; Fabio De-Giorgio; Xavier de la Torre; Monica Mazzarino; Matteo Marti; Francesco Botrè
Journal:  Drug Test Anal       Date:  2021-11-08       Impact factor: 3.234

6.  Khat Use: What Is the Problem and What Can Be Done?

Authors:  Yusuf Sheikh Omar; Anna Jenkins; Marieke van Regteren Altena; Harvey Tuck; Chris Hynan; Ahmed Tohow; Prem Chopra; David Castle
Journal:  Biomed Res Int       Date:  2015-05-03       Impact factor: 3.411

Review 7.  Synthetic cathinones: a new public health problem.

Authors:  Laurent Karila; Bruno Megarbane; Olivier Cottencin; Michel Lejoyeux
Journal:  Curr Neuropharmacol       Date:  2015-01       Impact factor: 7.363

8.  Before the ban--an exploratory study of a local khat market in East London, U.K.

Authors:  Saba Kassim; Asha Dalsania; Johan Nordgren; Axel Klein; Josh Hulbert
Journal:  Harm Reduct J       Date:  2015-06-12

9.  Khat (Catha edulis Forsk.) Dependence Potential and Pattern of Use in Saudi Arabia.

Authors:  Siddig Ibrahim Abdelwahab; Rashad Mohammed Alsanosy; Bahaa-Eldin E A Rahim; Syam Mohan; Sara Taha; Manal Mohamed Elhassan; Maged El-Setouhy
Journal:  Biomed Res Int       Date:  2015-08-24       Impact factor: 3.411

10.  Khat chewing and restrictive dietary behaviors are associated with anemia among pregnant women in high prevalence rural communities in eastern Ethiopia.

Authors:  Haji Kedir; Yemane Berhane; Alemayehu Worku
Journal:  PLoS One       Date:  2013-11-04       Impact factor: 3.240

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