Literature DB >> 20452220

NF-kappaB signaling modulation by EBV and KSHV.

Deilson Elgui de Oliveira1, Gianna Ballon, Ethel Cesarman.   

Abstract

The nuclear factor (NF)-kappaB signaling pathway is pivotal for immune system function. Not surprisingly, pathogenic microorganisms have developed strategies to subvert it. Two examples are Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus (KSHV), oncogenic gammaherpesviruses that establish a lifelong latent infection in their human hosts. The modulation of NF-kappaB signaling by EBV and KSHV is not only important for viral infection, but also contributes to the development of malignant neoplasia. This review explores the current knowledge of NF-kappaB modulation by EBV and KSHV, focusing on connections between viral biology and human carcinogenesis. Copyright 2010. Published by Elsevier Ltd.

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Year:  2010        PMID: 20452220     DOI: 10.1016/j.tim.2010.04.001

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  60 in total

Review 1.  Virus-encoded microRNAs.

Authors:  Adam Grundhoff; Christopher S Sullivan
Journal:  Virology       Date:  2011-01-31       Impact factor: 3.616

Review 2.  Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients.

Authors:  Ethel Cesarman
Journal:  Cancer Lett       Date:  2011-04-13       Impact factor: 8.679

Review 3.  Viral miRNAs and immune evasion.

Authors:  Isaac W Boss; Rolf Renne
Journal:  Biochim Biophys Acta       Date:  2011-07-05

4.  Oncogenic herpesviruses sending mixed signals.

Authors:  D Michiel Pegtel
Journal:  Proc Natl Acad Sci U S A       Date:  2013-07-19       Impact factor: 11.205

5.  Association of Kaposi’s sarcoma-associated herpesvirus (KSHV) with bladder cancer in Croatian patients.

Authors:  Martina Paradžik; Viljemka Bučević-Popović; Marijan Šitum; Crystal J Jaing; Marina Degoricija; Kevin S McLoughlin; Said I Ismail; Volga Punda-Polić; Janoš Terzić
Journal:  Tumour Biol       Date:  2014-01

6.  Role of IRF4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells.

Authors:  Adriana Forero; Patrick S Moore; Saumendra N Sarkar
Journal:  J Immunol       Date:  2013-06-26       Impact factor: 5.422

7.  Human renal carcinoma cells respond to Newcastle disease virus infection through activation of the p38 MAPK/NF-κB/IκBα pathway.

Authors:  Wei-Choong Ch'ng; Noraini Abd-Aziz; Meng-Hua Ong; Eric J Stanbridge; Norazizah Shafee
Journal:  Cell Oncol (Dordr)       Date:  2015-05-01       Impact factor: 6.730

8.  Identification of Target Genes Regulated by KSHV miRNAs in KSHV-Infected Lymphoma Cells.

Authors:  Liangliang Quan; Tao Qiu; Jiulong Liang; Miao Li; Yu Zhang; Kai Tao
Journal:  Pathol Oncol Res       Date:  2015-02-04       Impact factor: 3.201

Review 9.  Recent advances on viral manipulation of NF-κB signaling pathway.

Authors:  Jun Zhao; Shanping He; Arlet Minassian; Junhua Li; Pinghui Feng
Journal:  Curr Opin Virol       Date:  2015-09-15       Impact factor: 7.090

10.  Concurrent targeting of eicosanoid receptor 1/eicosanoid receptor 4 receptors and COX-2 induces synergistic apoptosis in Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus associated non-Hodgkin lymphoma cell lines.

Authors:  Arun George Paul; Bala Chandran; Neelam Sharma-Walia
Journal:  Transl Res       Date:  2013-03-20       Impact factor: 7.012

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