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Literature DB >> 20451977

The genetic and phenotypic basis of infertility in men with pediatric urologic disorders.

Michael H Hsieh¹, Adam Hollander, Dolores J Lamb, Paul J Turek.

Abstract

Male factor is a major component of infertility for many couples. The presence of congenital genitourinary anomalies in male partners can cause male infertility. We reviewed the state-of-the-art treatment and outcomes for male infertility caused by pediatric urologic disorders. Disorders were classified by whether they led to infertility through pre-testis, testicular, or post-testis effects. Despite the complexity of pediatric urologic disorders that can affect fertility, natural paternity and paternity through assisted reproductive technology are common. Given the significant recent advances in infertility treatments, paternity with many currently untreatable pediatric disorders is likely in the future. Copyright 2010 Elsevier Inc. All rights reserved.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2010 PMID： 20451977 PMCID： PMC2897955 DOI： 10.1016/j.urology.2010.03.011

Source DB: PubMed Journal: Urology ISSN： 0090-4295 Impact factor: 2.649

47 in total

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Journal: Nat Med Date: 2008-11-06 Impact factor: 53.440

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Authors: Jay D Raman; Peter N Schlegel
Journal: J Urol Date: 2003-10 Impact factor: 7.450