Literature DB >> 20451372

Nasopharyngeal carcinoma: the next challenges.

Albiruni R A Razak1, Lillian L Siu, Fei-Fei Liu, Emma Ito, Brian O'Sullivan, Kelvin Chan.   

Abstract

Nasopharyngeal carcinoma (NPC) differs from other head and neck cancers in its aetiology, epidemiology and potential therapeutic options. Despite cure for the majority of the patients, challenges still exist in the prevention of disease relapse, treatment of patients with refractory or metastatic NPC and the management of long-term toxicities. This article discusses the specific challenges in pushing the boundaries of NPC treatments further, with an emphasis on prognostic/predictive markers, molecularly targeted therapies, immunotherapies and the areas of interest with regard to long-term toxicities arising from therapeutic interventions. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20451372     DOI: 10.1016/j.ejca.2010.04.004

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0959-8049            Impact factor:   9.162


  116 in total

1.  An orthotopic model of metastatic nasopharyngeal carcinoma and its application in elucidating a therapeutic target that inhibits metastasis.

Authors:  Pamela A Smith; David Merritt; Leah Barr; David A Thorley-Lawson
Journal:  Genes Cancer       Date:  2011-11

2.  Elevated apolipoprotein A-I levels are associated with favorable prognosis in metastatic nasopharyngeal carcinoma.

Authors:  Rou Jiang; Zhong-Han Yang; Dong-Hua Luo; Ling Guo; Rui Sun; Qiu-Yan Chen; Pei-Yu Huang; Fang Qiu; Xiong Zou; Ka-Jia Cao; Hai-Qiang Mai; Xiang Guo; Chao-Nan Qian; Ming-Huang Hong; Ming-Yuan Chen
Journal:  Med Oncol       Date:  2014-07-15       Impact factor: 3.064

3.  Risk factors and prediction-score model for distant metastasis in nasopharyngeal carcinoma treated with intensity-modulated radiotherapy.

Authors:  An-Chuan Li; Wei-Wei Xiao; Lin Wang; Guan-Zhu Shen; An-An Xu; Yan-Qing Cao; Shao-Min Huang; Cheng-Guang Lin; Fei Han; Xiao-Wu Deng; Chong Zhao
Journal:  Tumour Biol       Date:  2015-05-27

4.  NEDD4 is involved in acquisition of epithelial-mesenchymal transition in cisplatin-resistant nasopharyngeal carcinoma cells.

Authors:  Shaoyan Feng; Guangwei Yang; Haidi Yang; Zibin Liang; Rongkai Zhang; Yunping Fan; Gehua Zhang
Journal:  Cell Cycle       Date:  2017-04-05       Impact factor: 4.534

5.  lncRNA C22orf32-1 contributes to the tumorigenesis of nasopharyngeal carcinoma.

Authors:  Guo-Hui Nie; Zhao Li; Hong-Fang Duan; Liang Luo; Hong-Yi Hu; Wei-Qiang Yang; Li-Ping Nie; Ru-Fei Zhu; Xiao-Fan Chen; Wei Zhang
Journal:  Oncol Lett       Date:  2017-04-11       Impact factor: 2.967

6.  Comparison of MRI, CT and 18F-FDG PET/CT in the diagnosis of local and metastatic of nasopharyngeal carcinomas: an updated meta analysis of clinical studies.

Authors:  Wang-Sheng Chen; Jian-Jun Li; Lan Hong; Zeng-Bao Xing; Fen Wang; Chang-Qing Li
Journal:  Am J Transl Res       Date:  2016-11-15       Impact factor: 4.060

7.  SP1-induced AFAP1-AS1 contributes to proliferation and invasion by regulating miR-497-5p/CELF1 pathway in nasopharyngeal carcinoma.

Authors:  Hui Jin; Gengtian Liang; Liping Yang; Li Liu; Binru Wang; Fengqin Yan
Journal:  Hum Cell       Date:  2021-01-05       Impact factor: 4.174

8.  γ-secretase inhibition combined with cisplatin enhances apoptosis of nasopharyngeal carcinoma cells.

Authors:  Jun-Xu Zhou; Ji-Bo Han; Shi-Ming Chen; Yu Xu; Yong-Gang Kong; Bo-Kui Xiao; Ze-Zhang Tao
Journal:  Exp Ther Med       Date:  2011-12-06       Impact factor: 2.447

9.  Radiomics Analysis of PET and CT Components of PET/CT Imaging Integrated with Clinical Parameters: Application to Prognosis for Nasopharyngeal Carcinoma.

Authors:  Wenbing Lv; Qingyu Yuan; Quanshi Wang; Jianhua Ma; Qianjin Feng; Wufan Chen; Arman Rahmim; Lijun Lu
Journal:  Mol Imaging Biol       Date:  2019-10       Impact factor: 3.488

10.  Radiotherapy combined docetaxel and oxaliplatin chemotherapy is effective in patients with locally advanced nasopharyngeal carcinoma.

Authors:  Feng Pan; Zhihua Ruan; Jianjun Li; Xueli Pang; Yanling Zhang; Lan Zou; Houjie Liang
Journal:  Med Oncol       Date:  2015-10-15       Impact factor: 3.064

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