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Literature DB >> 20451357

Stress, genetics and epigenetic effects on the neurobiology of suicidal behavior and depression.

Abstract

Alterations in a number of neurobiological systems have been associated with suicidal behavior including the serotonergic and noradrenergic systems and the hypothalamic-pituitary-adrenal axis. Altered functioning of these systems may stem from both genetic and developmental causes. Adversity in early-life has developmental consequences on these systems that persist into adulthood. Genetic differences may also contribute to alterations in functioning of neurobiological systems. Moreover, the interaction of early-life experiences of adversity and genetic vulnerability is increasingly thought to play a role, including via epigenetic mechanisms. (c) 2010 Elsevier Masson SAS. All rights reserved.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2010 PMID： 20451357 PMCID： PMC2896004 DOI： 10.1016/j.eurpsy.2010.01.009

Source DB: PubMed Journal: Eur Psychiatry ISSN： 0924-9338 Impact factor: 5.361

29 in total

Review 1. Genetics of suicide: a systematic review of twin studies.

Authors: Martin Voracek; Lisa Mariella Loibl
Journal: Wien Klin Wochenschr Date: 2007 Impact factor: 1.704

Review 2. Stress, genes and the biology of suicidal behavior.

Authors: Dianne Currier; J John Mann
Journal: Psychiatr Clin North Am Date: 2008-06

Review 3. Adverse childhood experiences and suicidal behavior.

Authors: Beth S Brodsky; Barbara Stanley
Journal: Psychiatr Clin North Am Date: 2008-06

4. Interaction between childhood trauma and serotonin transporter gene variation in suicide.

Authors: Alec Roy; Xian-Zhang Hu; Malvin N Janal; David Goldman
Journal: Neuropsychopharmacology Date: 2007-03-14 Impact factor: 7.853

5. Reported childhood abuse is associated with low serotonin transporter binding in vivo in major depressive disorder.

Authors: Jeffrey M Miller; Erin L Kinnally; R Todd Ogden; Maria A Oquendo; J John Mann; Ramin V Parsey
Journal: Synapse Date: 2009-07 Impact factor: 2.562

Review 6. Long story short: the serotonin transporter in emotion regulation and social cognition.

Authors: Turhan Canli; Klaus-Peter Lesch
Journal: Nat Neurosci Date: 2007-09 Impact factor: 24.884

Review 7. The role of dopamine and serotonin in suicidal behaviour and aggression.

Authors: Erik Ryding; Mats Lindström; Lil Träskman-Bendz
Journal: Prog Brain Res Date: 2008 Impact factor: 2.453

8. Genetic architecture of the human tryptophan hydroxylase 2 Gene: existence of neural isoforms and relevance for major depression.

Authors: F Haghighi; H Bach-Mizrachi; Y Y Huang; V Arango; S Shi; A J Dwork; G Rosoklija; H T Sheng; I Morozova; J Ju; J J Russo; J J Mann
Journal: Mol Psychiatry Date: 2008-01-08 Impact factor: 15.992

9. Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.

Authors: Rebekah G Bradley; Elisabeth B Binder; Michael P Epstein; Yilang Tang; Hemu P Nair; Wei Liu; Charles F Gillespie; Tiina Berg; Mark Evces; D Jeffrey Newport; Zachary N Stowe; Christine M Heim; Charles B Nemeroff; Ann Schwartz; Joseph F Cubells; Kerry J Ressler
Journal: Arch Gen Psychiatry Date: 2008-02

Review 10. The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis.

Authors: R Uher; P McGuffin
Journal: Mol Psychiatry Date: 2007-08-14 Impact factor: 15.992

41 in total

1. Genetic and environmental contributions to self-reported thoughts of self-harm and suicide.

Authors: Robert R Althoff; James J Hudziak; Gonneke Willemsen; Vicenta Hudziak; Meike Bartels; Dorret I Boomsma
Journal: Am J Med Genet B Neuropsychiatr Genet Date: 2011-12-07 Impact factor: 3.568

Review 2. Epidemiology of stress and asthma: from constricting communities and fragile families to epigenetics.

Authors: Rosalind J Wright
Journal: Immunol Allergy Clin North Am Date: 2011-02 Impact factor: 3.479

Review 3. Epigenetic pathways through which experiences become linked with biology.

Authors: Patrick O McGowan; Tania L Roth
Journal: Dev Psychopathol Date: 2015-05

Review 4. Epidemiology, neurobiology and pharmacological interventions related to suicide deaths and suicide attempts in bipolar disorder: Part I of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder.

Authors: Ayal Schaffer; Erkki T Isometsä; Leonardo Tondo; Doris H Moreno; Mark Sinyor; Lars Vedel Kessing; Gustavo Turecki; Abraham Weizman; Jean-Michel Azorin; Kyooseob Ha; Catherine Reis; Frederick Cassidy; Tina Goldstein; Zoltán Rihmer; Annette Beautrais; Yuan-Hwa Chou; Nancy Diazgranados; Anthony J Levitt; Carlos A Zarate; Lakshmi Yatham
Journal: Aust N Z J Psychiatry Date: 2015-07-16 Impact factor: 5.744