Hui-hua Wang1, Zheng-ping Wang. 1. Department of Maternity, The First People's Hospital of Tongxiang, Zhejiang 314500, China.
Abstract
OBJECTIVE: To evaluate the effect of different combined immunoprophylaxis delivery modes on mother to infant transmission of hepatitis B virus (HBV). METHODS: Six hundred and ninety-six relevant literatures were collected by systematic literature search. Meta-analysis was applied to seven selected literatures that met the criteria and to assess the influence on the infant HBV transmission via different delivery patterns by infants combined immunoprophylaxis. RESULTS: A total of 1435 cases from seven studies which met the criteria were included. The positive rate of HBV was 7.34% (61/831) among the 831 infants in the vaginal delivery group and 4.80% (29/604) among the 604 infants in the caesarean section group. There was no statistically difference between the two groups (OR = 0.70, 95%CI: 0.45 - 1.11, Z = 1.52, P = 0.13). CONCLUSION: There was no significant effect of delivery modes on infant infectious rate of HBV by infants' passive and active immunization.
OBJECTIVE: To evaluate the effect of different combined immunoprophylaxis delivery modes on mother to infant transmission of hepatitis B virus (HBV). METHODS: Six hundred and ninety-six relevant literatures were collected by systematic literature search. Meta-analysis was applied to seven selected literatures that met the criteria and to assess the influence on the infantHBV transmission via different delivery patterns by infants combined immunoprophylaxis. RESULTS: A total of 1435 cases from seven studies which met the criteria were included. The positive rate of HBV was 7.34% (61/831) among the 831 infants in the vaginal delivery group and 4.80% (29/604) among the 604 infants in the caesarean section group. There was no statistically difference between the two groups (OR = 0.70, 95%CI: 0.45 - 1.11, Z = 1.52, P = 0.13). CONCLUSION: There was no significant effect of delivery modes on infant infectious rate of HBV by infants' passive and active immunization.