Literature DB >> 20450378

Herpes simplex virus type 1 persists in the aged brain through hypothetical expression of accessory genes.

Isamu Mori1.   

Abstract

Herpes simplex virus type 1 persists in the brain of most aged individuals and may contribute to the pathogenesis of Alzheimer's disease. The virus likely utilizes accessory genes for neural spread within the nervous system and herpes simplex virus type 1 may regulate various host responses through an array of accessory genes. This mini-review focuses on these viral accessory genes that may shed light on the potential mechanisms of this enigmatic phenomenon in the elderly brain.

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Year:  2010        PMID: 20450378     DOI: 10.3109/13550281003739040

Source DB:  PubMed          Journal:  J Neurovirol        ISSN: 1355-0284            Impact factor:   2.643


  49 in total

1.  Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptide.

Authors:  D H Cribbs; B Y Azizeh; C W Cotman; F M LaFerla
Journal:  Biochemistry       Date:  2000-05-23       Impact factor: 3.162

2.  Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis.

Authors:  Luca Benetti; Bernard Roizman
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-10       Impact factor: 11.205

3.  HSV and glycoprotein J inhibit caspase activation and apoptosis induced by granzyme B or Fas.

Authors:  K R Jerome; Z Chen; R Lang; M R Torres; J Hofmeister; S Smith; R Fox; C J Froelich; L Corey
Journal:  J Immunol       Date:  2001-10-01       Impact factor: 5.422

4.  Productive herpes simplex virus in brain of elderly normal subjects and Alzheimer's disease patients.

Authors:  Matthew A Wozniak; Suzanne J Shipley; Marc Combrinck; Gordon K Wilcock; Ruth F Itzhaki
Journal:  J Med Virol       Date:  2005-02       Impact factor: 2.327

5.  The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase.

Authors:  B He; M Gross; B Roizman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-02-04       Impact factor: 11.205

6.  Herpes simplex virus infection causes cellular beta-amyloid accumulation and secretase upregulation.

Authors:  Matthew A Wozniak; Ruth F Itzhaki; Suzanne J Shipley; Curtis B Dobson
Journal:  Neurosci Lett       Date:  2007-10-13       Impact factor: 3.046

7.  CTL are inactivated by herpes simplex virus-infected cells expressing a viral protein kinase.

Authors:  Derek D Sloan; George Zahariadis; Christine M Posavad; Nichlos T Pate; Steven J Kussick; Keith R Jerome
Journal:  J Immunol       Date:  2003-12-15       Impact factor: 5.422

8.  Herpes simplex virus type 1 glycoprotein E mediates retrograde spread from epithelial cells to neurites.

Authors:  Helen M McGraw; Harvey M Friedman
Journal:  J Virol       Date:  2009-03-11       Impact factor: 5.103

9.  Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1.

Authors:  Joanne Trgovcich; David Johnson; Bernard Roizman
Journal:  J Virol       Date:  2002-07       Impact factor: 5.103

10.  Stimulation of enveloped virus infection by beta-amyloid fibrils.

Authors:  Woj M Wojtowicz; Michael Farzan; John L Joyal; Kara Carter; Gregory J Babcock; David I Israel; Joseph Sodroski; Tajib Mirzabekov
Journal:  J Biol Chem       Date:  2002-07-15       Impact factor: 5.157

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  3 in total

1.  Herpes Simplex Virus Type 1 Neuronal Infection Perturbs Golgi Apparatus Integrity through Activation of Src Tyrosine Kinase and Dyn-2 GTPase.

Authors:  Carolina Martin; Luis Leyton; Melissa Hott; Yennyfer Arancibia; Carlos Spichiger; Mark A McNiven; Felipe A Court; Margarita I Concha; Patricia V Burgos; Carola Otth
Journal:  Front Cell Infect Microbiol       Date:  2017-08-22       Impact factor: 5.293

Review 2.  Herpes Simplex Virus Type 1 Infection of the Central Nervous System: Insights Into Proposed Interrelationships With Neurodegenerative Disorders.

Authors:  Luisa F Duarte; Mónica A Farías; Diana M Álvarez; Susan M Bueno; Claudia A Riedel; Pablo A González
Journal:  Front Cell Neurosci       Date:  2019-02-26       Impact factor: 5.505

3.  A Possible Role for HSV-1-Specific Humoral Response and PILRA rs1859788 Polymorphism in the Pathogenesis of Parkinson's Disease.

Authors:  Simone Agostini; Roberta Mancuso; Andrea S Costa; Lorenzo A Citterio; Franca R Guerini; Mario Meloni; Jorge Navarro; Mario Clerici
Journal:  Vaccines (Basel)       Date:  2021-06-22
  3 in total

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