| Literature DB >> 20450378 |
Abstract
Herpes simplex virus type 1 persists in the brain of most aged individuals and may contribute to the pathogenesis of Alzheimer's disease. The virus likely utilizes accessory genes for neural spread within the nervous system and herpes simplex virus type 1 may regulate various host responses through an array of accessory genes. This mini-review focuses on these viral accessory genes that may shed light on the potential mechanisms of this enigmatic phenomenon in the elderly brain.Entities:
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Year: 2010 PMID: 20450378 DOI: 10.3109/13550281003739040
Source DB: PubMed Journal: J Neurovirol ISSN: 1355-0284 Impact factor: 2.643