Literature DB >> 2044984

Dispersion of retinal pigment epithelial cells from experimental retinal holes.

S A Bishara1, S M Buzney.   

Abstract

The effects of cryotherapy, transcleral massage, or directed irrigation on exposed retinal pigment epithelial (RPE) cells at the base of an experimental retinal hole were studied in living rabbit eyes. Cryotherapy or massage with or without vitrectomy failed to release RPE cells or result in preretinal membrane formation. Directed irrigation dispersed viable RPE cells into the vitreous and produced cellular precipitates with membranes on the inferior retina, although the membranes tended to regress within 6 weeks after surgery. These results suggest that healthy RPE cells at the base of retinal tears are not easily released into the vitreous and may not contribute to the formation of preretinal membranes found in proliferative vitreoretinopathy.

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Year:  1991        PMID: 2044984     DOI: 10.1007/bf00170557

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  14 in total

1.  Pathogenesis and classification of massive periretinal proliferation.

Authors:  R Machemer
Journal:  Br J Ophthalmol       Date:  1978-11       Impact factor: 4.638

2.  Specializations of the retinochoroidal juncture.

Authors:  H Miki; M B Bellhorn; P Henkind
Journal:  Invest Ophthalmol       Date:  1975-09

3.  Intravitreous fibronectin and platelet-derived growth factor. New model for traction retinal detachment.

Authors:  J H Yeo; J Sadeghi; P A Campochiaro; W R Green; B M Glaser
Journal:  Arch Ophthalmol       Date:  1986-03

4.  Pigment epithelium proliferation in retinal detachment (massive periretinal proliferation).

Authors:  R Machemer; H Laqua
Journal:  Am J Ophthalmol       Date:  1975-07       Impact factor: 5.258

5.  Further studies on a vitreous inhibitor of endothelial cell proliferation.

Authors:  B Jacobson; D Sullivan; L Raymond; P K Basu; S M Hasany
Journal:  Exp Eye Res       Date:  1983-03       Impact factor: 3.467

6.  The rate and route of fluid resorption from the subretinal space of the rabbit.

Authors:  D A Frambach; M F Marmor
Journal:  Invest Ophthalmol Vis Sci       Date:  1982-03       Impact factor: 4.799

7.  Isolation and identification of stimulatory and inhibitory cell growth factors in bovine vitreous.

Authors:  L Raymond; B Jacobson
Journal:  Exp Eye Res       Date:  1982-02       Impact factor: 3.467

8.  A comparison of different cellular inocula in an experimental model of massive periretinal proliferation.

Authors:  D M Fastenberg; K R Diddie; N Sorgente; S J Ryan
Journal:  Am J Ophthalmol       Date:  1982-05       Impact factor: 5.258

9.  The importance of fluid absorption, traction, intraocular currents, and chorioretinal scars in the therapy of rhegmatogenous retinal detachments. XLI Edward Jackson memorial lecture.

Authors:  R Machemer
Journal:  Am J Ophthalmol       Date:  1984-12-15       Impact factor: 5.258

10.  Simulation of massive periretinal proliferation by autotransplantation of retinal pigment epithelial cells in rabbits.

Authors:  N D Radtke; Y Tano; D Chandler; R Machemer
Journal:  Am J Ophthalmol       Date:  1981-01       Impact factor: 5.258

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