Literature DB >> 2044976

Daunomycin and silicone oil for the treatment of proliferative vitreoretinopathy.

P Wiedemann1, C Leinung, R D Hilgers, K Heimann.   

Abstract

We describe the long-term results after treatment of 68 eyes showing advanced stages of proliferative vitreoretinopathy with vitrectomy, daunomycin perfusion, and silicone-oil injection. Six reoperations were performed. After 18 months, 73% of the eyes showed no signs of retinal detachment and 89% had a visual acuity of greater than 20/800. These results are better than those reported in previously published studies. Whether this improvement was due to the daunomycin treatment or to more aggressive surgical techniques such as retinotomies remains to be answered by a randomized trial.

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Year:  1991        PMID： 2044976     DOI： 10.1007/bf00170548

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN： 0721-832X            Impact factor:   3.117


  11 in total

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Journal:  Am J Ophthalmol       Date:  1988-03-15       Impact factor: 5.258

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Journal:  Ophthalmology       Date:  1984-02       Impact factor: 12.079

7.  Long-term results of successful vitrectomy with silicone oil for advanced proliferative vitreoretinopathy.

Authors:  C H Sell; B W McCuen; M B Landers; R Machemer
Journal:  Am J Ophthalmol       Date:  1987-01-15       Impact factor: 5.258

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Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1982       Impact factor: 3.117

9.  Intraocular daunorubicin for the treatment and prophylaxis of traumatic proliferative vitreoretinopathy.

Authors:  P Wiedemann; K Lemmen; R Schmiedl; K Heimann
Journal:  Am J Ophthalmol       Date:  1987-07-15       Impact factor: 5.258

10.  A fluorescein angiographic study on patients with proliferative vitreoretinopathy treated by vitrectomy and intraocular daunomycin.

Authors:  P Wiedemann; P Y Evans; R Wiedemann; R Meyer-Schwickerath; K Heimann
Journal:  Int Ophthalmol       Date:  1989-05       Impact factor: 2.031
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  14 in total

1.  Cytotoxic effects of antiproliferative agents on human retinal glial cells in vitro.

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Journal:  Int Ophthalmol       Date:  2001       Impact factor: 2.031

Review 2.  Proliferative vitreoretinopathy: pathobiology, surgical management, and adjunctive treatment.

Authors:  D G Charteris
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Authors:  P K Leaver
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Review 6.  [Pharmacological approach to treatment of proliferative vitreoretinopathy].

Authors:  C S Priglinger; S Priglinger
Journal:  Ophthalmologe       Date:  2013-10       Impact factor: 1.059

7.  Growth inhibition of human Tenon's capsule fibroblasts and rabbit dermal fibroblasts with non-carcinogenic N-alkylated anthracyclines.

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Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1994-06       Impact factor: 3.117

8.  Corticosteroids and daunomycin in the prevention of experimental proliferative vitreoretinopathy induced by macrophages.

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Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1993-02       Impact factor: 3.117

9.  Ocular toxicity of daunomycin: effects of subdivided doses on the rabbit retina after vitreous gas compression.

Authors:  U H Steinhorst; D L Hatchell; E P Chen; R Machemer
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