Literature DB >> 20448974

Boiling water-catalyzed neutral and selective N-Boc deprotection.

Jia Wang1, Yan-Liang Liang, Jin Qu.   

Abstract

A general protocol for removing Boc groups from various types of nitrogen is reported and a preliminary investigation of the reaction mechanism indicates that water acts as a dual acid/base catalyst at elevated temperature.

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Year:  2009        PMID： 20448974     DOI： 10.1039/b910239f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  Design, Synthesis and Biological Evaluation of Prodrugs of 666-15 as Inhibitors of CREB-Mediated Gene Transcription.

Authors:  Jiangling Peng; Mark Miller; Bingbing X Li; Xiangshu Xiao
Journal:  ACS Med Chem Lett       Date:  2022-02-17       Impact factor: 4.632

2.  Overaccumulation of γ-Glutamylcysteine in a Jasmonate-Hypersensitive Arabidopsis Mutant Causes Jasmonate-Dependent Growth Inhibition.

Authors:  Hsin-Ho Wei; Martha Rowe; Jean-Jack M Riethoven; Ryan Grove; Jiri Adamec; Yusuke Jikumaru; Paul Staswick
Journal:  Plant Physiol       Date:  2015-08-17       Impact factor: 8.340

3.  Halisphingosines A and B, modified sphingoid bases from Haliclona tubifera. Assignment of configuration by circular dichroism and van't Hoff's principle of optical superposition.

Authors:  Tadeusz F Molinski; Renata Biegelmeyer; E Paige Stout; Xiao Wang; Mario L C Frota; Amelia T Henriques
Journal:  J Nat Prod       Date:  2012-12-26       Impact factor: 4.050

4.  Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY.

Authors:  Seung-Hwa Kwak; Won Young Lim; Aili Hao; Ellene H Mashalidis; Do-Yeon Kwon; Pyeonghwa Jeong; Mi Jung Kim; Seok-Yong Lee; Jiyong Hong
Journal:  Eur J Med Chem       Date:  2021-02-06       Impact factor: 6.514

Review 5.  Combining the benefits of homogeneous and heterogeneous catalysis with tunable solvents and nearcritical water.

Authors:  Ali Z Fadhel; Pamela Pollet; Charles L Liotta; Charles A Eckert
Journal:  Molecules       Date:  2010-11-16       Impact factor: 4.411

6.  Mild deprotection of the N-tert-butyloxycarbonyl (N-Boc) group using oxalyl chloride.

Authors:  Nathaniel George; Samuel Ofori; Sean Parkin; Samuel G Awuah
Journal:  RSC Adv       Date:  2020-06-23       Impact factor: 4.036

7.  Constrained Dipeptide Surrogates: 5- and 7-Hydroxy Indolizidin-2-one Amino Acid Synthesis from Iodolactonization of Dehydro-2,8-diamino Azelates.

Authors:  Ramakotaiah Mulamreddy; William D Lubell
Journal:  Molecules       Date:  2021-12-23       Impact factor: 4.411

8.  Fluorous-assisted chemoenzymatic synthesis of heparan sulfate oligosaccharides.

Authors:  Chao Cai; Demetria M Dickinson; Lingyun Li; Sayaka Masuko; Matt Suflita; Victor Schultz; Shawn D Nelson; Ujjwal Bhaskar; Jian Liu; Robert J Linhardt
Journal:  Org Lett       Date:  2014-04-04       Impact factor: 6.005

9.  Periodic Mesoporous Organosilica Nanoparticles with BOC Group, towards HIFU Responsive Agents.

Authors:  Hao Li; Carolina Gascó; Anthony Delalande; Clarence Charnay; Laurence Raehm; Patrick Midoux; Chantal Pichon; Roser Pleixats; Jean-Olivier Durand
Journal:  Molecules       Date:  2020-02-21       Impact factor: 4.411

10.  Covalent Inhibition of the Histamine H3 Receptor.

Authors:  Gábor Wágner; Tamara A M Mocking; Albert J Kooistra; Inna Slynko; Péter Ábrányi-Balogh; György M Keserű; Maikel Wijtmans; Henry F Vischer; Iwan J P de Esch; Rob Leurs
Journal:  Molecules       Date:  2019-12-11       Impact factor: 4.411
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