Literature DB >> 20447566

Hypoxia-regulated angiogenic inhibitors.

Angela Messmer-Blust1, Xiaojin An, Jian Li.   

Abstract

The regulation of angiogenesis by hypoxia is an essential homeostatic mechanism that depends on a precise balance between positive and negative angiogenic regulatory molecules. Proangiogenic factors are well characterized; however, several in vivo and in vitro studies indicate that there are feedback mechanisms in place to inhibit angiogenesis during hypoxia. Understanding the signaling pathways leading to the negative feedback of angiogenesis will undoubtedly provide important tools to develop novel therapeutic strategies not only to enhance the angiogenic response in coronary artery disease but also to hinder deregulated angiogenesis in tumorigenesis. Copyright 2009 Elsevier Inc. All rights reserved.

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Year:  2009        PMID： 20447566      PMCID： PMC2866290          DOI： 10.1016/j.tcm.2010.02.006

Source DB:  PubMed          Journal:  Trends Cardiovasc Med        ISSN： 1050-1738            Impact factor:   6.677


  33 in total

1.  RGS5, a hypoxia-inducible apoptotic stimulator in endothelial cells.

Authors:  Yi Jin; Xiaojin An; Zelian Ye; Brittany Cully; Jiaping Wu; Jian Li
Journal:  J Biol Chem       Date:  2009-06-29       Impact factor: 5.157

2.  Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis.

Authors:  Zhao-Jun Liu; Takashi Shirakawa; Yan Li; Akinobu Soma; Masahiro Oka; G Paolo Dotto; Ronald M Fairman; Omaida C Velazquez; Meenhard Herlyn
Journal:  Mol Cell Biol       Date:  2003-01       Impact factor: 4.272

Review 3.  HIF-1: mediator of physiological and pathophysiological responses to hypoxia.

Authors:  G L Semenza
Journal:  J Appl Physiol (1985)       Date:  2000-04

4.  Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress.

Authors:  S F Yan; T Fujita; J Lu; K Okada; Y Shan Zou; N Mackman; D J Pinsky; D M Stern
Journal:  Nat Med       Date:  2000-12       Impact factor: 53.440

5.  A comparison of aorta and vena cava medial message expression by cDNA array analysis identifies a set of 68 consistently differentially expressed genes, all in aortic media.

Authors:  L D Adams; R L Geary; B McManus; S M Schwartz
Journal:  Circ Res       Date:  2000-09-29       Impact factor: 17.367

6.  PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.

Authors:  G Xenaki; T Ontikatze; R Rajendran; I J Stratford; C Dive; M Krstic-Demonacos; C Demonacos
Journal:  Oncogene       Date:  2008-06-23       Impact factor: 9.867

7.  BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF.

Authors:  Shilpa Kothari; Jeannick Cizeau; Eileen McMillan-Ward; Sara J Israels; Michelle Bailes; Karen Ens; Lorrie A Kirshenbaum; Spencer B Gibson
Journal:  Oncogene       Date:  2003-07-24       Impact factor: 9.867

8.  Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium.

Authors:  Hai Tao Yuan; Eliyahu V Khankin; S Ananth Karumanchi; Samir M Parikh
Journal:  Mol Cell Biol       Date:  2009-02-17       Impact factor: 4.272

9.  Response gene to complement 32, a novel hypoxia-regulated angiogenic inhibitor.

Authors:  Xiaojin An; Yi Jin; Hongnian Guo; Shi-Yin Foo; Brittany L Cully; Jiaping Wu; Huiyan Zeng; Anthony Rosenzweig; Jian Li
Journal:  Circulation       Date:  2009-08-03       Impact factor: 29.690

10.  Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling.

Authors:  S E Bell; A Mavila; R Salazar; K J Bayless; S Kanagala; S A Maxwell; G E Davis
Journal:  J Cell Sci       Date:  2001-08       Impact factor: 5.285
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  12 in total

1.  IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis.

Authors:  Chunyang Zhang; Ling Lu; Yun Li; Xianlei Wang; Jianfeng Zhou; Yunzhang Liu; Ping Fu; Marisa A Gallicchio; Leon A Bach; Cunming Duan
Journal:  Int J Cancer       Date:  2011-08-05       Impact factor: 7.396

Review 2.  Pleiotropic effects of herbs characterized with blood-activating and stasis-resolving functions on angiogenesis.

Authors:  Li Tao; Sheng Wang; Yang Zhao; Ai-Yun Wang; Lei Zhang; Jun-Shan Ruan; Fang-Tian Fan; Yu-Ping Liu; Yao Li; Zhi-Qiang Yue; Wen-Hui Qian; Wen-Xing Chen; Yin Lu
Journal:  Chin J Integr Med       Date:  2016-06-29       Impact factor: 1.978

3.  HIF-1α represses the expression of the angiogenesis inhibitor thrombospondin-2.

Authors:  Susan C MacLauchlan; Nicole E Calabro; Yan Huang; Meenakshi Krishna; Tara Bancroft; Tanuj Sharma; Jun Yu; William C Sessa; Frank Giordano; Themis R Kyriakides
Journal:  Matrix Biol       Date:  2017-08-05       Impact factor: 11.583

4.  The Expression of IGFBP6 after Spinal Cord Injury: Implications for Neuronal Apoptosis.

Authors:  Song Wang; Yonghua Liu; Chunshuai Wu; Weijuan Zhao; Jinlong Zhang; Guofeng Bao; Guanhua Xu; Yuyu Sun; Jiajia Chen; Zhiming Cui
Journal:  Neurochem Res       Date:  2016-11-26       Impact factor: 3.996

5.  Recent insights into the actions of IGFBP-6.

Authors:  Leon A Bach
Journal:  J Cell Commun Signal       Date:  2015-03-26       Impact factor: 5.782

6.  Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1.

Authors:  Raquel Bienes-Martínez; Angel Ordóñez; Mónica Feijoo-Cuaresma; María Corral-Escariz; Gloria Mateo; Olga Stenina; Benilde Jiménez; María J Calzada
Journal:  Sci Rep       Date:  2012-11-09       Impact factor: 4.379

7.  Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye.

Authors:  Toshihide Kurihara; Peter D Westenskow; Tim U Krohne; Edith Aguilar; Randall S Johnson; Martin Friedlander
Journal:  J Cell Biol       Date:  2011-11-14       Impact factor: 10.539

8.  Effect of LLLT on endothelial cells culture.

Authors:  Krzysztof Góralczyk; Justyna Szymańska; Małgorzata Łukowicz; Ewelina Drela; Roman Kotzbach; Mariusz Dubiel; Małgorzata Michalska; Barbara Góralczyk; Andrzej Zając; Danuta Rość
Journal:  Lasers Med Sci       Date:  2014-09-18       Impact factor: 3.161

9.  Effects of Modest Hypoxia and Exercise on Cardiac Function, Sleep-Activity, Negative Geotaxis Behavior of Aged Female Drosophila.

Authors:  Qiu Fang Li; Hui Wang; Lan Zheng; Fan Yang; Han Zhe Li; Jin Xiu Li; Dan Cheng; Kai Lu; Yang Liu
Journal:  Front Physiol       Date:  2020-01-21       Impact factor: 4.566

10.  Circ_0068655 Promotes Cardiomyocyte Apoptosis via miR-498/PAWR Axis.

Authors:  Qiaoying Chai; Mingqi Zheng; Le Wang; Mei Wei; Yajuan Yin; Fangfang Ma; Xinping Li; Haijun Zhang; Gang Liu
Journal:  Tissue Eng Regen Med       Date:  2020-08-06       Impact factor: 4.169
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