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Literature DB >> 2044701

Mastoparan induces hypothermia in mice.

Abstract

The polypeptide mastoparan, isolated from the venom of the Oriental Hornet, Vespa orientalis, induces hypothermia in white mice 15 minutes after its intraperitoneal injection. The hypothermic effect is induced by mastoparan obtained from different hornet and wasp venoms. The normal murine core temperature is lowered by mastoparan from 38 degrees C to as far as 33 degrees C. This lowering lasts for one hour and is reversible.

Entities: Chemical Disease Species

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Year: 1991 PMID： 2044701 DOI： 10.1007/bf01959944

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

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References

22 in total

1. EFFECTS ON TEMPERATURE OF AMINES INJECTED INTO THE CEREBRAL VENTRICLES. A NEW CONCEPT OF TEMPERATURE REGULATION.

Authors: W FELDBERG; R D MYERS
Journal: J Physiol Date: 1964-09 Impact factor: 5.182

Review 2. CNS effects of peripherally administered brain peptides.

Authors: A J Kastin; R D Olson; A V Schally; D H Coy
Journal: Life Sci Date: 1979-07-30 Impact factor: 5.037

3. Kidney changes in mice due to oriental hornet (Vpespa orientalis) venom: histological and electron microscopical study.

Authors: U Sandbank; J Ishay; S Gitter
Journal: Acta Pharmacol Toxicol (Copenh) Date: 1973

4. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors: U K Laemmli
Journal: Nature Date: 1970-08-15 Impact factor: 49.962

5. The amino acid sequences around the reactive serine and histidine residues of the chymotrypsin-like protease from the hornet, Vespa orientalis.

Authors: K D Jany; K Bekelaer; J Ishay
Journal: Biochim Biophys Acta Date: 1981-03-27

6. Deoxyribonucleases of the Oriental hornet (Vespa orientalis) venom--II. Partial characterization and effects in vivo on insects and mammals.

Authors: B Ring; H Slor; B Perna; J S Ishay
Journal: Toxicon Date: 1978 Impact factor: 3.033

Mastoparan induces hypothermia in mice.

1. EFFECTS ON TEMPERATURE OF AMINES INJECTED INTO THE CEREBRAL VENTRICLES. A NEW CONCEPT OF TEMPERATURE REGULATION.

Review 2. CNS effects of peripherally administered brain peptides.

3. Kidney changes in mice due to oriental hornet (Vpespa orientalis) venom: histological and electron microscopical study.

4. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

5. The amino acid sequences around the reactive serine and histidine residues of the chymotrypsin-like protease from the hornet, Vespa orientalis.

6. Deoxyribonucleases of the Oriental hornet (Vespa orientalis) venom--II. Partial characterization and effects in vivo on insects and mammals.

7. Hypothermia induced in mice by injection of venom sac extract of hornets (Vespa orientalis, vespinae: hymenoptera).

8. Cholecystokinin octapeptide, caerulein and caerulein analogues: effects on thermoregulation in the mouse.

9. Alarm substances as toxicants of the oriental hornet, Vespa orientalis.

10. Pharmacological activity of oriental hornet (Vespa orientalis) venom.