Yong Min Kim1, Soo Young Lee, Hyoung Jun Koh. 1. The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 134 Shinchon-dong, Sodaemoon-gu, Seoul, 120-752, Korea.
Abstract
BACKGROUND: To evaluate the role of preoperative optical coherence tomography (OCT), multifocal electroretinography (mfERG), and fluorescein angiography (FA) as prognostic factors for vision after pars plana vitrectomy (PPV) in diabetic macular edema (DME). METHODS: Thirty-five eyes of 34 patients who underwent PPV were retrospectively reviewed. Best-corrected visual acuity (VA) was measured at baseline, and at 3, 6, and 9 months after surgery. Patients were categorized into two groups according to the final VA. Group 1 consisted of eyes with 0.2 or more logMAR lines of visual recovery, the rest of the eyes being placed in group 2. Preoperative FA findings, central macular thickness and mfERG responses at the central macula were evaluated to determine their effect on visual outcome. RESULTS: Eighteen eyes showed improved VA after PPV, and were classified into group 1. Seventeen eyes were placed in group 2. The presence of macular ischemia did not affect the postoperative visual outcome between the groups, although a trend was noted toward macular ischemia with delayed implicit time. P1 implicit time at the central seven hexagons (eccentricity of 0-5 degrees ) was the only statistically significant factor predicting unfavorable visual outcome. There was significantly delayed implicit time in group 2 patients compared with those of group 1. MfERG responses at other retinal eccentricities and central macular thickness did not show significant association with visual prognosis. CONCLUSIONS: Preoperative mfERG parameters, especially the implicit time, can be useful indicators for predicting functional visual prognosis after PPV in DME.
BACKGROUND: To evaluate the role of preoperative optical coherence tomography (OCT), multifocal electroretinography (mfERG), and fluorescein angiography (FA) as prognostic factors for vision after pars plana vitrectomy (PPV) in diabetic macular edema (DME). METHODS: Thirty-five eyes of 34 patients who underwent PPV were retrospectively reviewed. Best-corrected visual acuity (VA) was measured at baseline, and at 3, 6, and 9 months after surgery. Patients were categorized into two groups according to the final VA. Group 1 consisted of eyes with 0.2 or more logMAR lines of visual recovery, the rest of the eyes being placed in group 2. Preoperative FA findings, central macular thickness and mfERG responses at the central macula were evaluated to determine their effect on visual outcome. RESULTS: Eighteen eyes showed improved VA after PPV, and were classified into group 1. Seventeen eyes were placed in group 2. The presence of macular ischemia did not affect the postoperative visual outcome between the groups, although a trend was noted toward macular ischemia with delayed implicit time. P1 implicit time at the central seven hexagons (eccentricity of 0-5 degrees ) was the only statistically significant factor predicting unfavorable visual outcome. There was significantly delayed implicit time in group 2 patients compared with those of group 1. MfERG responses at other retinal eccentricities and central macular thickness did not show significant association with visual prognosis. CONCLUSIONS: Preoperative mfERG parameters, especially the implicit time, can be useful indicators for predicting functional visual prognosis after PPV in DME.
Authors: S D Pendergast; T S Hassan; G A Williams; M S Cox; R R Margherio; P J Ferrone; B R Garretson; M T Trese Journal: Am J Ophthalmol Date: 2000-08 Impact factor: 5.258
Authors: David J Browning; Rajendra S Apte; Susan B Bressler; Kakarla V Chalam; Ronald P Danis; Matthew D Davis; Craig Kollman; Haijing Qin; Srinivas Sadda; Ingrid U Scott Journal: Retina Date: 2009-03 Impact factor: 4.256